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QCBio Research Seminar: Arjun Bhattacharya (Pasaniuc)

April 2, 2021 @ 11:00 am

TITLE: “Distal mediator-enriched placental transcriptome-wide association studies reveal genetic mechanisms supporting the  Developmental Origins of Health and Disease.”

ABSTRACT: As the master regulator of the intrauterine environment, the placenta is core to the Developmental Origins of Health and Disease (DOHaD) but is understudied in large consortia of tissue-specific gene and trait regulation. We performed distal mediator-enriched transcriptome-wide association studies for 40 health outcomes across 5 categories, using gene expression models trained from multi-omic data from the Extremely Low Gestational Age Newborn Study. I will discuss some of the novel methods we leverage in this analysis and the implications our computational and experimental results suggest on placental biology and health outcomes.

Details

Date:
April 2, 2021
Time:
11:00 am
Event Category:

Venue

ZOOM
CA United States
View Venue Website

Organizer

QCBio

Details

Date:
April 2, 2021
Time:
11:00 am
Event Category:

Venue

ZOOM
CA United States
View Venue Website

Organizer

QCBio