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QCBio Research Seminar: Chloe Yap (Gandal), Visiting Graduate Student, University of Queensland

November 17 @ 12:00 pm - 12:30 pm

TITLE: “Restricted diet drives autism gut-microbiome associations, and other tales from the Australian Autism Biobank”

ABSTRACT: The Australian Autism Biobank (AAB) is an initiative of the Autism CRC – the first national, cooperative research effort focused on autism across the lifespan. The AAB recruited a total of ~2,500 autistic children, family members, and unrelated undiagnosed children, and couples deep phenotypic information with multi-omic datasets (SNP genotyping, stool metagenomics, DNA methylation, metabolomics, WGS). One particularly controversial area in the field has been the potential causal contribution of the gut microbiome to autism. I will present results from one of the largest metagenomics study of the autism stool microbiome to date (n=246, including 99 children diagnosed with autism). We propose a model whereby microbiome changes in autistic children may reflect consequences of behaviour and dietary preferences, and we caution against undue emphasis on the microbiome having an upstream role in autism.

 

Details

Date:
November 17
Time:
12:00 pm - 12:30 pm
Event Category:

Organizer

QCBio

Venue

Boyer 159
611 Charles E. Young Dr. E.
Los Angeles, CA 90095 United States
+ Google Map
Website:
https://qcb.ucla.edu

Details

Date:
November 17
Time:
12:00 pm - 12:30 pm
Event Category:

Organizer

QCBio

Venue

Boyer 159
611 Charles E. Young Dr. E.
Los Angeles, CA 90095 United States
+ Google Map
Website:
https://qcb.ucla.edu