Loading Events

« All Events

  • This event has passed.

QCBio Research Seminar: Maria Izabel Alves Cavassim (Lohmueller)

February 19 @ 11:00 am - 11:30 am

TITLE: The evolution and co-evolution of PRDM9 across vertebrates

ABSTRACT: In sexually reproducing organisms, meiotic recombination is initiated by the deliberate infliction of numerous double-strand breaks (DSBs) in the genome, the repair of which yields crossover and non-crossover resolutions. In most mammals, these DSBs are specified through the binding of PRDM9 and the deposition of H3K4me3 and H3K36me3 marks. Despite its evolutionary importance, PRDM9 has been independently lost numerous times across vertebrate’s evolution. Here, we take advantage of the multiple independent PRDM9 losses to infer the co-evolution of PRDM9 with other meiosis-related genes.

Details

Date:
February 19
Time:
11:00 am - 11:30 am
Event Category:

Venue

ZOOM
CA United States
Website:
ucla.zoom.us

Organizer

QCBio

Details

Date:
February 19
Time:
11:00 am - 11:30 am
Event Category:

Venue

ZOOM
CA United States
Website:
ucla.zoom.us

Organizer

QCBio