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X-ORIGINAL-URL:https://qcb.ucla.edu
X-WR-CALDESC:Events for Institute for Quantitative and Computational Biosciences
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20241007T120000
DTEND;TZID=America/Los_Angeles:20241007T130000
DTSTAMP:20260516T065907
CREATED:20241002T165755Z
LAST-MODIFIED:20241002T182126Z
UID:26948-1728302400-1728306000@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Erik Andersen\, PhD\, Professor\, Johns Hopkins University
DESCRIPTION:TITLE: “Mechanisms of differences in gene expression and organismal traits caused by structural variation (both real and imagined)” \nHosted by Leonid Kruglyak for Genetics & Genomics
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-erik-andersen-phd-professor-johns-hopkins-university/
LOCATION:Boyer Hall 159
CATEGORIES:QCBio Seminar Series,Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2024/10/andersen.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20241014T120000
DTEND;TZID=America/Los_Angeles:20241014T130000
DTSTAMP:20260516T065907
CREATED:20241002T170419Z
LAST-MODIFIED:20241002T170419Z
UID:26952-1728907200-1728910800@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Ludmil Alexandrov\, Phd\, Professor\, Cellular and Molecular Medicine\, UC San Diego
DESCRIPTION:TITLE: TBD \nHosted by Paul Spellman for Genetics & Genomics
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-ludmil-alexandrov-phd-professor-cellular-and-molecular-medicine-uc-san-diego/
LOCATION:Boyer Hall 159
CATEGORIES:QCBio Seminar Series,Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2024/10/Alexandrov.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20241021T120000
DTEND;TZID=America/Los_Angeles:20241021T130000
DTSTAMP:20260516T065907
CREATED:20241002T180358Z
LAST-MODIFIED:20241002T180358Z
UID:26960-1729512000-1729515600@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Yin Yi\, PhD\, Assistant Professor\, UCLA
DESCRIPTION:TITLE: TBD \nHosted by Kirk Lohmueller for Bioinformatics
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-yin-yi-phd-assistant-professor-ucla/
LOCATION:Boyer Hall 159
CATEGORIES:QCBio Seminar Series,Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2024/10/Seminar-Series-Poster-–-Fall-2024-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20241022T123000
DTEND;TZID=America/Los_Angeles:20241022T133000
DTSTAMP:20260516T065907
CREATED:20241011T162102Z
LAST-MODIFIED:20241011T162102Z
UID:27013-1729600200-1729603800@qcb.ucla.edu
SUMMARY:QCBio Research Seminar: Rizal Hariadi\, Associate Professor\, Department of Physics and Biodesign Institute\, Arizona State University
DESCRIPTION:TITLE: Sensing and applying multi-axial tension to biomolecules using molecular devices built from DNA. \nABSTRACT: DNA nanotechnology enables the construction of molecular devices for diverse biomedical applications. By leveraging DNA’s exquisite positional control\, researchers can engineer sophisticated nanostructures that execute a range of tasks. In this talk\, I will present 2 DNA-based devices: an amphiphilic double-stranded DNA sensor for non-destructive detection of cytosolic biomarkers and a DNA origami platform for multi-axial mechanical manipulation of biomolecules. In the first part of my talk\, I will show synthetic transmembrane devices inspired by G protein-coupled receptors (GPCRs) that transduce signals across cell membranes. These amphiphilic DNA nanodevices detect specific intracellular oligonucleotides\, generating fluorescent signals without cell lysis and genetic engineering. In the second half of the talk\, I will present some recent results on a Holliday junction\, a model system in biophysics\, under multi-axial tension using the Multi-Axial Entropic Spring Tweezer along Rigid Origami (MAESTRO). This molecular tool\, which exploits the entropic elasticity of single-stranded DNA\, uncovers the non-ergodicity of Holliday junction dynamics. The talk concludes with a discussion on the potential applications of these devices\, including their use in high-throughput single-molecule biophysics of integrin signaling\, cryo-EM structural studies of integrins under tension\, and live-cell isolation targeting RNA markers.
URL:https://qcb.ucla.edu/event/qcbio-research-seminar-rizal-hariadi-associate-professor-department-of-physics-and-biodesign-institute-arizona-state-university/
LOCATION:Boyer Hall 159
CATEGORIES:QCBio Seminar Series,Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2024/10/Rizal_Hariadi.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20241028T120000
DTEND;TZID=America/Los_Angeles:20241028T130000
DTSTAMP:20260516T065907
CREATED:20241002T180736Z
LAST-MODIFIED:20241002T180736Z
UID:26964-1730116800-1730120400@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Jayashree Kalpathy-Cramer\, PhD\, Professor\, Ophthalmology; Chief\, Division of Artificial Medical Intelligence\, Ophtalmology; Director\, Health Informatics\, CCTSI; University of Colorado - Anschutz Medical Center
DESCRIPTION:TITLE: TBD \nHosted by William Hsu for Medical Informatics
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-jayashree-kalpathy-cramer-phd-professor-ophthalmology-chief-division-of-artificial-medical-intelligence-ophtalmology-director-health-info/
LOCATION:Boyer Hall 159
CATEGORIES:QCBio Seminar Series,Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2024/10/Seminar-Series-Poster-–-Fall-2024-2.jpg
END:VEVENT
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