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X-ORIGINAL-URL:https://qcb.ucla.edu
X-WR-CALDESC:Events for Institute for Quantitative and Computational Biosciences
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20250210T120000
DTEND;TZID=America/Los_Angeles:20250210T130000
DTSTAMP:20260412T080559
CREATED:20250103T010516Z
LAST-MODIFIED:20250103T010516Z
UID:27351-1739188800-1739192400@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Karthik Sarma\, MD\, PhD\, Chief Technology Officer\, SimX; Computational Medical Scientist and Clinical Psychiatrist\, UCSF
DESCRIPTION:TITLE: “TBD”
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-karthik-sarma-md-phd-chief-technology-officer-simx-computational-medical-scientist-and-clinical-psychiatrist-ucsf/
LOCATION:Boyer Hall 159
CATEGORIES:Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2025/01/Seminar-Series-Poster-–-W25-2.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20250203T120000
DTEND;TZID=America/Los_Angeles:20250203T130000
DTSTAMP:20260412T080559
CREATED:20250103T010243Z
LAST-MODIFIED:20250103T010243Z
UID:27347-1738584000-1738587600@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Katie Hoadley\, PhD\, Associate Professor\, Genetics\, UNC-Chapel Hill
DESCRIPTION:TITLE: “TBD”
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-katie-hoadley-phd-associate-professor-genetics-unc-chapel-hill/
LOCATION:Boyer Hall 159
CATEGORIES:Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2025/01/Seminar-Series-Poster-–-W25-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20250127T120000
DTEND;TZID=America/Los_Angeles:20250127T130000
DTSTAMP:20260412T080559
CREATED:20250103T005843Z
LAST-MODIFIED:20250103T005843Z
UID:27341-1737979200-1737982800@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Gary Bader\, PhD\, Professor\, The Donnelly Centre\, University of Toronto
DESCRIPTION:TITLE: “TBD”
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-gary-bader-phd-professor-the-donnelly-centre-university-of-toronto/
LOCATION:Boyer Hall 159
CATEGORIES:Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2025/01/Seminar-Series-Poster-–-W25.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20250113T120000
DTEND;TZID=America/Los_Angeles:20250113T130000
DTSTAMP:20260412T080559
CREATED:20250103T005607Z
LAST-MODIFIED:20250103T005607Z
UID:27337-1736769600-1736773200@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Imon Banerjee\, PhD\, Associate Professor & Consultant\, Department of Radiology\, Department of Artificial Intelligence & Informatics (AI&I)\, and Lead AI Scientist\, Mayo Clinic Arizona
DESCRIPTION:TITLE: “TBD”
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-imon-banerjee-phd-associate-professor-consultant-department-of-radiology-department-of-artificial-intelligence-informatics-aiam/
LOCATION:Boyer Hall 159
CATEGORIES:Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2025/01/Imon.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20250106T120000
DTEND;TZID=America/Los_Angeles:20250106T130000
DTSTAMP:20260412T080559
CREATED:20250103T005110Z
LAST-MODIFIED:20250103T010024Z
UID:27332-1736164800-1736168400@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Iman Hajirasouliha\, PhD.\, Associate Professor of Computational Genomics in Biomedicine\, Weill Cornell Medicine
DESCRIPTION:TITLE: “Somatic structural variation detection with deep learning and a core modular analysis pipeline“
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-iman-hajirasouliha-p-h-d-associate-professor-of-computational-genomics-in-biomedicine-weill-cornell-medicine/
LOCATION:Boyer Hall 159
CATEGORIES:Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2025/01/Hajirasouliha.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20241202T120000
DTEND;TZID=America/Los_Angeles:20241202T130000
DTSTAMP:20260412T080559
CREATED:20241002T181856Z
LAST-MODIFIED:20241002T181902Z
UID:26980-1733140800-1733144400@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Stephen Montgomery\, PhD\, Stanford Medicine Endowed Professor of Pathology and Professor of Genetics\, Biomedical Data Science and Computer Science\, Stanford University
DESCRIPTION:TITLE: TBD \nHosted by Brunilda Balliu for Genetics & Genomics
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-stephen-montgomery-phd-stanford-medicine-endowed-professor-of-pathology-and-professor-of-genetics-biomedical-data-science-and-computer-science/
LOCATION:Boyer Hall 159
CATEGORIES:QCBio Seminar Series,Research Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20241125T120000
DTEND;TZID=America/Los_Angeles:20241125T130000
DTSTAMP:20260412T080559
CREATED:20241002T181607Z
LAST-MODIFIED:20241002T181607Z
UID:26976-1732536000-1732539600@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Andrea Ganna\, PhD\, Associate Professor at FIMM and HiLIFE; Research Associate\, Harvard Medical School and Massachusetts General Hospital
DESCRIPTION:TITLE: TBD \nHosted by Sriram Sankararaman for Bioinformatics
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-andrea-ganna-phd-associate-professor-at-fimm-and-hilife-research-associate-harvard-medical-school-and-massachusetts-general-hospital/
LOCATION:Boyer Hall 159
CATEGORIES:QCBio Seminar Series,Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2024/10/Seminar-Series-Poster-–-Fall-2024-5.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20241118T120000
DTEND;TZID=America/Los_Angeles:20241118T130000
DTSTAMP:20260412T080559
CREATED:20241002T181338Z
LAST-MODIFIED:20241002T181338Z
UID:26972-1731931200-1731934800@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Brenna M. Henn\, PdD\, Associate Professor\, Department of Anthropology; Co-Director\, Northern Cape Tuberculosis Project\, UC Davis
DESCRIPTION:TITLE: TBD \nHosted by Noah Naitlen for Genetics & Genomics
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-brenna-m-henn-pdd-associate-professor-department-of-anthropology-co-director-northern-cape-tuberculosis-project-uc-davis/
LOCATION:Boyer Hall 159
CATEGORIES:QCBio Seminar Series,Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2024/10/Seminar-Series-Poster-–-Fall-2024-4.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20241104T120000
DTEND;TZID=America/Los_Angeles:20241104T130000
DTSTAMP:20260412T080559
CREATED:20241002T181018Z
LAST-MODIFIED:20241002T181018Z
UID:26968-1730721600-1730725200@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Julia Salzman\, PhD\, Associate Professor\, Department of Biomedical Data Science and of Biochemistry\, Stanford University
DESCRIPTION:TITLE: TBD \nHosted by Nandita Garud for Bioinformatics
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-julia-salzman-phd-associate-professor-department-of-biomedical-data-science-and-of-biochemistry-stanford-university/
LOCATION:Boyer Hall 159
CATEGORIES:QCBio Seminar Series,Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2024/10/Seminar-Series-Poster-–-Fall-2024-3.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20241028T120000
DTEND;TZID=America/Los_Angeles:20241028T130000
DTSTAMP:20260412T080559
CREATED:20241002T180736Z
LAST-MODIFIED:20241002T180736Z
UID:26964-1730116800-1730120400@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Jayashree Kalpathy-Cramer\, PhD\, Professor\, Ophthalmology; Chief\, Division of Artificial Medical Intelligence\, Ophtalmology; Director\, Health Informatics\, CCTSI; University of Colorado - Anschutz Medical Center
DESCRIPTION:TITLE: TBD \nHosted by William Hsu for Medical Informatics
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-jayashree-kalpathy-cramer-phd-professor-ophthalmology-chief-division-of-artificial-medical-intelligence-ophtalmology-director-health-info/
LOCATION:Boyer Hall 159
CATEGORIES:QCBio Seminar Series,Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2024/10/Seminar-Series-Poster-–-Fall-2024-2.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20241022T123000
DTEND;TZID=America/Los_Angeles:20241022T133000
DTSTAMP:20260412T080559
CREATED:20241011T162102Z
LAST-MODIFIED:20241011T162102Z
UID:27013-1729600200-1729603800@qcb.ucla.edu
SUMMARY:QCBio Research Seminar: Rizal Hariadi\, Associate Professor\, Department of Physics and Biodesign Institute\, Arizona State University
DESCRIPTION:TITLE: Sensing and applying multi-axial tension to biomolecules using molecular devices built from DNA. \nABSTRACT: DNA nanotechnology enables the construction of molecular devices for diverse biomedical applications. By leveraging DNA’s exquisite positional control\, researchers can engineer sophisticated nanostructures that execute a range of tasks. In this talk\, I will present 2 DNA-based devices: an amphiphilic double-stranded DNA sensor for non-destructive detection of cytosolic biomarkers and a DNA origami platform for multi-axial mechanical manipulation of biomolecules. In the first part of my talk\, I will show synthetic transmembrane devices inspired by G protein-coupled receptors (GPCRs) that transduce signals across cell membranes. These amphiphilic DNA nanodevices detect specific intracellular oligonucleotides\, generating fluorescent signals without cell lysis and genetic engineering. In the second half of the talk\, I will present some recent results on a Holliday junction\, a model system in biophysics\, under multi-axial tension using the Multi-Axial Entropic Spring Tweezer along Rigid Origami (MAESTRO). This molecular tool\, which exploits the entropic elasticity of single-stranded DNA\, uncovers the non-ergodicity of Holliday junction dynamics. The talk concludes with a discussion on the potential applications of these devices\, including their use in high-throughput single-molecule biophysics of integrin signaling\, cryo-EM structural studies of integrins under tension\, and live-cell isolation targeting RNA markers.
URL:https://qcb.ucla.edu/event/qcbio-research-seminar-rizal-hariadi-associate-professor-department-of-physics-and-biodesign-institute-arizona-state-university/
LOCATION:Boyer Hall 159
CATEGORIES:QCBio Seminar Series,Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2024/10/Rizal_Hariadi.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20241021T120000
DTEND;TZID=America/Los_Angeles:20241021T130000
DTSTAMP:20260412T080559
CREATED:20241002T180358Z
LAST-MODIFIED:20241002T180358Z
UID:26960-1729512000-1729515600@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Yin Yi\, PhD\, Assistant Professor\, UCLA
DESCRIPTION:TITLE: TBD \nHosted by Kirk Lohmueller for Bioinformatics
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-yin-yi-phd-assistant-professor-ucla/
LOCATION:Boyer Hall 159
CATEGORIES:QCBio Seminar Series,Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2024/10/Seminar-Series-Poster-–-Fall-2024-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20241014T120000
DTEND;TZID=America/Los_Angeles:20241014T130000
DTSTAMP:20260412T080559
CREATED:20241002T170419Z
LAST-MODIFIED:20241002T170419Z
UID:26952-1728907200-1728910800@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Ludmil Alexandrov\, Phd\, Professor\, Cellular and Molecular Medicine\, UC San Diego
DESCRIPTION:TITLE: TBD \nHosted by Paul Spellman for Genetics & Genomics
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-ludmil-alexandrov-phd-professor-cellular-and-molecular-medicine-uc-san-diego/
LOCATION:Boyer Hall 159
CATEGORIES:QCBio Seminar Series,Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2024/10/Alexandrov.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20241007T120000
DTEND;TZID=America/Los_Angeles:20241007T130000
DTSTAMP:20260412T080559
CREATED:20241002T165755Z
LAST-MODIFIED:20241002T182126Z
UID:26948-1728302400-1728306000@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Erik Andersen\, PhD\, Professor\, Johns Hopkins University
DESCRIPTION:TITLE: “Mechanisms of differences in gene expression and organismal traits caused by structural variation (both real and imagined)” \nHosted by Leonid Kruglyak for Genetics & Genomics
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-erik-andersen-phd-professor-johns-hopkins-university/
LOCATION:Boyer Hall 159
CATEGORIES:QCBio Seminar Series,Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2024/10/andersen.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240930T120000
DTEND;TZID=America/Los_Angeles:20240930T130000
DTSTAMP:20260412T080559
CREATED:20241002T170647Z
LAST-MODIFIED:20241002T170647Z
UID:26956-1727697600-1727701200@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Armita Nourmohammad\, PhD\, Associate Professor\, University of Washington
DESCRIPTION:TITLE: TBD \nHosted by Alexander Hoffmann for Bioinformatics
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-armita-nourmohammad-phd-associate-professor-university-of-washington/
LOCATION:Boyer Hall 159
CATEGORIES:QCBio Seminar Series,Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2024/10/Seminar-Series-Poster-–-Fall-2024.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240530T173000
DTEND;TZID=America/Los_Angeles:20240530T190000
DTSTAMP:20260412T080559
CREATED:20240425T144458Z
LAST-MODIFIED:20240425T144458Z
UID:26564-1717090200-1717095600@qcb.ucla.edu
SUMMARY:QCBio Special Evening Lecture: Dr. Michael Elowitz\, Assistant Adjunct Professor\, Biological Chemistry\, UCLA
DESCRIPTION:TITLE: “Designing synthetic circuits for biological understanding and therapeutic applications”
URL:https://qcb.ucla.edu/event/qcbio-special-evening-lecture-dr-michael-elowitz-assistant-adjunct-professor-biological-chemistry-ucla/
LOCATION:Boyer Hall 159
CATEGORIES:Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2024/04/Elowitz.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240520T120000
DTEND;TZID=America/Los_Angeles:20240520T130000
DTSTAMP:20260412T080559
CREATED:20240407T154633Z
LAST-MODIFIED:20240407T154633Z
UID:26492-1716206400-1716210000@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Jana Lipkova\, PhD\, Assistant Professor of Pathology\, UC Irvine
DESCRIPTION:TITLE: “AI-based multimodal data fusion in oncology” \nHosted by William Hsu for Medical Informatics and UCLA JCCC \n 
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-jana-lipkova-phd-assistant-professor-of-pathology-uc-irvine/
LOCATION:Boyer Hall 159
CATEGORIES:Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2024/04/Jana.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240513T120000
DTEND;TZID=America/Los_Angeles:20240513T130000
DTSTAMP:20260412T080559
CREATED:20240407T154357Z
LAST-MODIFIED:20240407T154357Z
UID:26488-1715601600-1715605200@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Ghayda Mirzaa\, MD\, Associate Professor\, Pediatrics and Medical Genetics\, Seattle Children's Hospital
DESCRIPTION:TITLE: “The genetics of pediatric surgical epilepsy disorders: successes\, challenges and future avenues” \nHosted by Saitta Sulagna for Genetics & Genomics
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-ghayda-mirzaa-md-associate-professor-pediatrics-and-medical-genetics-seattle-childrens-hospital/
LOCATION:Boyer 159\, 611 Charles E. Young Dr. E.\, Los Angeles\, CA\, 90095\, United States
CATEGORIES:Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2024/04/Ghayda.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240429T140000
DTEND;TZID=America/Los_Angeles:20240429T140000
DTSTAMP:20260412T080559
CREATED:20240407T153716Z
LAST-MODIFIED:20240407T153716Z
UID:26480-1714399200-1714399200@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Omolola Ogunyemi\, PhD\, FACMI\, Director\, Center for Biomedical Informatics\, Professor\, Preventive & Social Medicine Charles Drew University
DESCRIPTION:TITLE: “AI and the Healthcare Safety Net” \nHosted by William Hsu for Medical Informatics
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-omolola-ogunyemi-phd-facmi-director-center-for-biomedical-informatics-professor-preventive-social-medicine-charles-drew-university/
LOCATION:529 Boyer Hall\, 611 Charles E Young Dr E\,\, Los Angeles\, CA\, 90095\, United States
CATEGORIES:Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2024/04/Omo.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240422T120000
DTEND;TZID=America/Los_Angeles:20240422T130000
DTSTAMP:20260412T080559
CREATED:20240407T153357Z
LAST-MODIFIED:20240407T153357Z
UID:26476-1713787200-1713790800@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Mia Levine\, PhD\, Associate Professor\, University of Pennsylvania
DESCRIPTION:TITLE: “Intra-genomic conflict and the evolution of genome integrity” \nHosted by Kirk Lohmueller for Genetics & Genomics
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-mia-levine-phd-associate-professor-university-of-pennsylvania/
LOCATION:Boyer 159
CATEGORIES:Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2024/04/MIA.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240415T120000
DTEND;TZID=America/Los_Angeles:20240415T130000
DTSTAMP:20260412T080559
CREATED:20240407T153129Z
LAST-MODIFIED:20240407T153129Z
UID:26472-1713182400-1713186000@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Chongzhi Zang\, PhD\, Associate Professor\, University of Virginia
DESCRIPTION:TITLE: “Computational Methods for Trancriptional Regulation” \nHosted by Jingyi Jessica Li for Bioinformatics
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-chongzhi-zang-phd-associate-professor-university-of-virginia/
LOCATION:Boyer 159
CATEGORIES:Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2024/04/Chongzhi.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240408T120000
DTEND;TZID=America/Los_Angeles:20240408T130000
DTSTAMP:20260412T080559
CREATED:20240407T152731Z
LAST-MODIFIED:20240407T152731Z
UID:26467-1712577600-1712581200@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Barbara Cheifet\, PhD\, Editor in Chief\, Nature Biotechnology
DESCRIPTION:TITLE: “Publishing for Impact” \nHosted by Jingyi Jessica Li for Bioinformatics
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-barbara-cheifet-phd-editor-in-chief-nature-biotechnology/
LOCATION:Boyer 159\, 611 Charles E. Young Dr. E.\, Los Angeles\, CA\, 90095\, United States
CATEGORIES:Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2024/04/Barbara.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20240401T120000
DTEND;TZID=America/Los_Angeles:20240401T130000
DTSTAMP:20260412T080559
CREATED:20240401T144912Z
LAST-MODIFIED:20240401T145230Z
UID:26433-1711972800-1711976400@qcb.ucla.edu
SUMMARY:Frontiers in Computational Biosciences Seminar Series: Alexis Battle\, PhD\, Professor\, Biomedical Engineering\, Computer Science and Genetics Medicine Director\, Malone Center for Engineering in Healthcare\, Johns Hopkins University
DESCRIPTION:TITLE: “Multi-omic and temporal data for rare and common genetic variation”
URL:https://qcb.ucla.edu/event/frontiers-in-computational-biosciences-seminar-series-alexis-battle-phd-professor-biomedical-engineering-computer-science-and-genetics-medicine-director-malone-center-for-engineering-in-healthcar/
LOCATION:Boyer 159
CATEGORIES:Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2024/04/ALEXIS.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230724T110000
DTEND;TZID=America/Los_Angeles:20230724T120000
DTSTAMP:20260412T080559
CREATED:20230719T153531Z
LAST-MODIFIED:20230719T153531Z
UID:24891-1690196400-1690200000@qcb.ucla.edu
SUMMARY:QCBio Research Seminar: Andras Gyorgy\, Assistant Professor of Electrical Engineering and Bioengineering - NYU Abu Dhabi
DESCRIPTION:TITLE: “Inducible plasmid copy number control and a blueprint for a synthetic genetic feedback optimizer” \nABSTRACT: The ability to control gene expression has been paradigm shifting for all areas of biological research\, especially for synthetic biology. This talk will focus on two recent advancements in gene expression control. First\, TULIP (TUnable Ligand Inducible Plasmid) is presented: a self-contained plasmid with inducible copy number control\, designed for portability across various Escherichia coli strains commonly used for cloning\, protein expression\, and metabolic engineering. As demonstrated through multiple application examples\, flexible plasmid copy number control via TULIP accelerates the design and optimization of gene circuits\, enables efficient probing of metabolic burden\, and facilitates the prototyping and recycling of modules in different genetic contexts. Second\, the blueprint of a genetic feedback module is presented to optimize a broadly defined performance metric by adjusting the production and decay rate of a set of regulator species. The optimizer can be implemented by combining available synthetic biology parts and components\, and it can be readily integrated with existing pathways and genetically encoded biosensors to ensure its successful deployment in a variety of settings when relying on mass action kinetics-based dynamics and parameter values typical in Escherichia coli.
URL:https://qcb.ucla.edu/event/qcbio-research-seminar-andras-gyorgy-assistant-professor-of-electrical-engineering-and-bioengineering-nyu-abu-dhabi/
LOCATION:Boyer Hall 130
CATEGORIES:Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2023/07/Andras-Gyorgy-7.24.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230721T160000
DTEND;TZID=America/Los_Angeles:20230721T170000
DTSTAMP:20260412T080559
CREATED:20230719T152504Z
LAST-MODIFIED:20230719T152504Z
UID:24886-1689955200-1689958800@qcb.ucla.edu
SUMMARY:BIG Summer Research Seminar: Jimmy Hu\, Assistant Professor in the Division of Oral Biology & Medicine at the UCLA School of Dentistry
DESCRIPTION:TITLE: “Building a tooth from transcriptome to tissue morphogenesis” \nABSTRACT: During craniofacial development\, the oral epithelium begins as a morphologically homogeneous tissue that gives rise to locally complex structures\, including the teeth\, salivary glands\, and taste buds. How the epithelium is initially patterned and later shaped to generate diverse organ and cell types remains largely unknown. To elucidate the genetic programs that direct the formation of distinct oral epithelial populations\, we mapped the transcriptional landscape of embryonic day (E) 12 mouse mandibular epithelia at single cell resolution. Our analysis identified key transcription factors and gene regulatory networks that define different epithelial cell types. By examining the spatiotemporal patterning process along the oral-aboral axis\, our results inform a model where the dental field is progressively confined to its position by the formation of the aboral epithelium anteriorly and the non-dental oral epithelium posteriorly. As dental suprabasal cells are enriched with genes related to actomyosin-based motility\, we next studied mutant embryos lacking non-muscle myosin II to explore the roles of cellular forces during tooth morphogenesis. We found that myosin II is critical for maintaining cell-cell adhesion and for efficient cellular movement that drives dental epithelial invagination. Together\, our results describe the transcriptional regulation during oral epithelial patterning and unveil an actomyosin-based mechanism that promotes tooth invagination.
URL:https://qcb.ucla.edu/event/big-summer-research-seminar-jimmy-hu-assistant-professor-in-the-division-of-oral-biology-medicine-at-the-ucla-school-of-dentistry/
LOCATION:Boyer 159\, 611 Charles E. Young Dr. E.\, Los Angeles\, CA\, 90095\, United States
CATEGORIES:Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2023/07/Jimmy-Hu.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230714T160000
DTEND;TZID=America/Los_Angeles:20230714T170000
DTSTAMP:20260412T080559
CREATED:20230711T184053Z
LAST-MODIFIED:20230711T184148Z
UID:24861-1689350400-1689354000@qcb.ucla.edu
SUMMARY:BIG Summer Research Seminar: Xianghong Jasmine Zhou\, Professor\, Pathology and Laboratory Medicine at UCLA
DESCRIPTION:TITLE: “Liquid Biopsies for Precision Oncology.” \nABSTRACT: Liquid biopsies are new diagnostic approaches to profile molecular features of solid tumors by blood\, saliva\, urine\, and other body fluids. Such approaches offer non-invasive options in early cancer detection\, tumor sampling\, continuous monitoring\, and designing personalized therapeutic options. Therefore\, liquid biopsies have the potential to transform the field of clinical oncology. Recently\, cell-free DNA analysis from a simple blood draw received enormous attention for its promise in these applications. In this talk\, we will discuss several novel computational and experimental technologies on using cell-free DNA for the detection and monitoring of cancer and other diseases.
URL:https://qcb.ucla.edu/event/big-summer-research-seminar-xianghong-jasmine-zhou-professor-pathology-and-laboratory-medicine-at-ucla/
LOCATION:Boyer Hall 159
CATEGORIES:Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2023/07/Jasmine_round-3.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230707T160000
DTEND;TZID=America/Los_Angeles:20230707T170000
DTSTAMP:20260412T080559
CREATED:20230627T234736Z
LAST-MODIFIED:20230627T234745Z
UID:24835-1688745600-1688749200@qcb.ucla.edu
SUMMARY:BIG Summer Research Seminar: Xia Yang\, Professor\, Integrative Biology and Physiology Molecular and Medical Pharmacology at UCLA
DESCRIPTION:TITLE: “Single Cell Multiomics Integration to Understand Complex Diseases.” \nABSTRACT: Recent advances in single cell multiomics technologies such as single cell RNA-seq\, single cell ATAC-seq\, and spatial transcriptomics have brought enormous opportunities that enable our understanding of the molecular underpinnings of pathophysiology at a single cell or cell type resolution. However\, integrative analysis across single cell multiomics domains has proven challenging.  I will introduce our recent efforts in single cell multiomics integration and gene regulatory network modeling\, present computational tools to carry out these analyses\, and showcase application examples in studies of various complex diseases. \n 
URL:https://qcb.ucla.edu/event/big-summer-research-seminar-xia-yang-professor-integrative-biology-and-physiology-molecular-and-medical-pharmacology-at-ucla/
LOCATION:Boyer 159\, 611 Charles E. Young Dr. E.\, Los Angeles\, CA\, 90095\, United States
CATEGORIES:Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2023/06/Xia-Yang-Ph.D..jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230630T160000
DTEND;TZID=America/Los_Angeles:20230630T170000
DTSTAMP:20260412T080559
CREATED:20230627T234352Z
LAST-MODIFIED:20230627T234352Z
UID:24831-1688140800-1688144400@qcb.ucla.edu
SUMMARY:BIG Summer Research Seminar: Eric Deeds\, Associate Professor\, Integrative Biology & Physiology - Vice Chair\, Life Sciences Core at UCLA
DESCRIPTION:TITLE: “A lack of distinct cellular identities in scRNA-seq data: revisiting Waddington’s landscape.” \nABSTRACT: Single-cell RNA sequencing is revolutionizing our understanding of development\, differentiation and disease. Analysis of this data is often challenging\, however\, and tasks like clustering cells to uncover distinct cellular identities sometimes yields results that fail to align with existing biological knowledge. We analyzed publicly available data where the cell identity for each cell is known a priori\, and found that cells of very different types and lineages do not occupy distinct regions of gene expression space. Rather\, cells from different lineages overlap extensively with one another\, significantly complicating attempts to recover distinct identities within the data. Indeed\, our analysis of available epigenetic data for a wide variety of tissues and organisms revealed these data are not consistent with the predictions of Waddington’s landscape\, suggesting a need to revisit our picture of gene expression changes during differentiation and development. \n 
URL:https://qcb.ucla.edu/event/big-summer-research-seminar-eric-deeds-associate-professor-integrative-biology-physiology-vice-chair-life-sciences-core-at-ucla/
LOCATION:Boyer 159\, 611 Charles E. Young Dr. E.\, Los Angeles\, CA\, 90095\, United States
CATEGORIES:Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2023/06/eric-deeds.jpeg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230623T163000
DTEND;TZID=America/Los_Angeles:20230623T170000
DTSTAMP:20260412T080559
CREATED:20230621T151413Z
LAST-MODIFIED:20230627T233954Z
UID:24821-1687537800-1687539600@qcb.ucla.edu
SUMMARY:BIG Summer Research Seminar: Brunilda Balliu\, Assistant Professor in the Departments of Pathology & Laboratory Medicine and Computational Medicine at UCLA
DESCRIPTION:TITLE: “FastGxC: a statistical framework for mapping context-specific regulatory variants using bulk and single-cell RNA-seq data.” \nABSTRACT: Recent studies suggest that context-specific eQTLs underlie genetic risk factors for complex diseases. However\, methods for identifying them are still nascent\, limiting their comprehensive characterization and downstream interpretation of disease-associated variants. In this talk\, I will introduce FastGxC\, a method to efficiently and powerfully map context-specific eQTLs by leveraging the correlation structure of bulk multi-tissue and single-cell RNA-seq studies. We applied FastGxC to simulated and real bulk and single-cell RNA-Seq data sets and show that FastGxC is orders of magnitude more powerful and computationally efficient than existing eQTL mapping approaches\, making previously yearlong computations possible in minutes. In addition\, FastGxC provides a three-fold increase in precision to identify relevant tissues and cell types for GWAS variants than standard eQTL mapping approaches. \n\nhttps://qcb.ucla.edu/wp-content/uploads/sites/14/2023/06/Brunilda-Balliu-62323.mp4
URL:https://qcb.ucla.edu/event/big-summer-research-seminar-brunilda-balliu-assistant-professor-in-the-departments-of-pathology-laboratory-medicine-and-computational-medicine-at-ucla/
LOCATION:ZOOM\, CA\, United States
CATEGORIES:Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2023/06/Brunilda-Balliu-PhD-11r5x7.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230324T123000
DTEND;TZID=America/Los_Angeles:20230324T130000
DTSTAMP:20260412T080559
CREATED:20230319T153305Z
LAST-MODIFIED:20230327T174010Z
UID:24633-1679661000-1679662800@qcb.ucla.edu
SUMMARY:QCBio Research Seminar: Nicholas Wang (Boutros)\, Grad Student\, Bioinformatics
DESCRIPTION:TITLE: “Germline structural variants shape prostate cancer clinical and molecular evolution.” \nABSTRACT: Inherited genetic variation profoundly influences cancer risk and outcome. While the impact of germline single nucleotide polymorphisms has been well-studied in several cancer types\, the effects of germline structural variants (gSVs) on cancer biology and clinical outcomes is largely unknown. From our cohort of 300 men with localized\, intermediate risk prostate cancer\, we identified 6\,003 gSVs present in at least 3% of patients\, with 48 associated with recurrent somatic alterations or clinical outcome. Of these\, ~50% associated with expression of nearby genes or intersected with exons or regulatory regions. Using external cohorts\, we validated three gSVs that were strongly associated with poor clinical outcomes\, including an inversion at chr14q24.1 present in ~20% of patients. Notably\, a strong synergistic effect on outcome was observed in patients with somatic TP53 alterations or high genomic instability\, defining a new aggressive prostate cancer subtype with chr14INV as a novel\, recurrent biomarker. \nhttps://qcb.ucla.edu/wp-content/uploads/sites/14/2023/03/Nicholas-Wang-32423.mp4
URL:https://qcb.ucla.edu/event/qcbio-research-seminar-nicholas-wang-boutros-grad-student-bioinformatics-p/
LOCATION:ZOOM\, CA\, United States
CATEGORIES:Research Seminars
ATTACH;FMTTYPE=image/jpeg:https://wp-misc.lifesci.ucla.edu/qcb/wp-content/uploads/sites/14/2023/03/Nicholas-Wang.jpg
END:VEVENT
END:VCALENDAR