Institute for Quantitative and Computational Biosciences

Frontiers in Computational Biosciences Seminar Series: Lixing Yang, PhD, Assistant Professor of Ben May Department of Cancer Research - University of Chicago
2025-06-02 12:00 - 13:00 (America/Los_Angeles) | Boyer Hall 159
TITLE: “The Causes and Consequences of Somatic Structural Variations in Human Cancer”

W36: Mergeomics for Multiomics Integration
2025-05-20 09:00 - 2025-05-22 12:00 | 529 Boyer Hall, 611 Charles E Young Dr E,, Los Angeles, CA, 90095, United States
Mergeomics is a computational tool designed to elucidate the underlying pathways, networks, and key regulators of complex diseases by integrating multi-omics data (genomics, transcriptomics, epigenomics, proteomics, etc). With use of integrative omics concepts and network modeling methods, this tool can uncover disease-associated gene sets and biological pathways across omics layers and can identify key drivers within gene regulatory networks or protein-protein interaction networks. In this workshop, we will first discuss the background, omics integration concepts, and capabilities of Mergeomics as well as the key analytical functions and various inputs that are commonly used. Next, we will demonstrate how this web tool can be used to analyze a complex disease by walking participants through each step within the Mergeomics web server and explain how to interpret the results.

Frontiers in Computational Biosciences Seminar Series: Carl Veller, PhD, Assistant Professor of Ecology & Evolution - University of Chicago
2025-05-19 12:00 - 13:00 | Boyer Hall 159
TITLE: “Chromosome-scale drift under stabilizing selection, with evolutionary implications”

Frontiers in Computational Biosciences Seminar Series: Roy Wollman, PhD, Professor, Biochemistry, Structural and Computational Biology, Systems Biology and Biological Regulation - UCLA
2025-05-12 12:00 - 13:00 | Boyer Hall 159
TITLE: “Spatial Single-Cell Mapping of Transcriptional Differences Across Genetic Backgrounds in Mouse Brains”

W6: BS-DNA Methylation Analysis with Hoffman2 and R
2025-05-06 09:00 - 2025-05-08 12:00 | 529 Boyer Hall, 611 Charles E Young Dr E,, Los Angeles, CA, 90095, United States
This workshop will introduce the basic principles of DNA methylation and briefly describe available methods for DNA methylation assessment, focusing on bisulfite sequencing (BS-Seq). We will cover the principles of BSseq preprocessing, alignment and methylation calling, differential methylation analysis, annotation and visualization. Attendees will have the opportunity to work on real DNA methylation data provided by the instructor and run the analysis on Hoffman2 and locally. Attendees need to have a basic knowledge in UNIX commands and R programming for this workshop. No previous experience with NGS or DNA methylation analysis is necessary.

Frontiers in Computational Biosciences Seminar Series: Mark Gerstein, PhD, Albert L Williams Professor of Biomedical Informatics and Professor of Molecular Biophysics & Biochemistry, of Computer Science, and of Statistics & Data Science - Yale
2025-05-05 12:00 - 13:00 | Boyer Hall 159
TITLE: “TBD”

Webinar: Big data for novel diagnostics and therapeutics
2025-04-29 17:30 - 18:30 | ZOOM, CA, United States
Fueled by technological innovations, online databases and algorithmic developments, biomedical research is rapidly becoming a data science. In this webinar, three of the most innovative UCLA faculty will share their perspectives on how biological big data are enabling their research. We will hear about robotic instrumentation that generate big data about drugs and genes, how diverse datasets can be integrated to identify patterns that inform novel diagnostics, and how shared databases can be leveraged to identify new disease insights from existing drugs.
Big Data for Novel Diagnostics and Therapeutics
a conversation featuring
Xia Yang
Professor, Integrative Biology and Physiology
Professor, Molecular and Medical Pharmacology
Robert D. Damoiseaux
Professor, Molecular and Medical Pharmacology
Professor, Bioengineering
Jennifer L. Wilson
Assistant Professor, Bioengineering
moderated by
Alexander Hoffmann
Director, Institute for Quantitative and Computational Biosciences
Asher Professor of Microbiology, Department of Microbiology, Immunology and Molecular Genetics

Frontiers in Computational Biosciences Seminar Series: Tiffani Bright, PhD, Co-Director, Center for Artificial Intelligence Research and Education; Assistant Professor, Department of Computational Biomedicine - Cedars-Sinai Medical Center
2025-04-28 12:00 - 17:00 | ZOOM, CA, United States
TITLE: “Fair AI for Health: Reducing Bias in Predictive Models”

Frontiers in Computational Biosciences Seminar Series: Justin Sonnenburg, PhD, Alex and Susie Algard Endowed Professor, Microbiology & Immunology - Stanford University
2025-04-21 12:30 - 13:00 | Boyer Hall 159
TITLE: “The Predicament of the Industrialized Gut Microbiome”

Frontiers in Computational Biosciences Seminar Series: Xuebing Wu, PhD, Assistant Professor of Medical Sciences - Columbia University
2025-04-14 12:00 - 13:00 | Boyer Hall 159
TITLE: “Illuminating the Twilight Zone: The Noncoding Genome Lost in Translation”

https://qcb.ucla.edu/wp-content/uploads/sites/14/2025/03/Wu_Xuebing_Edited.mp4

Frontiers in Computational Biosciences Seminar Series: Adam Yala, PhD, Assistant Professor of Computational Precision Heath, Statistics and EECS - UC Berkeley and UCSF
2025-04-07 12:00 - 13:00 | Boyer Hall 159
TITLE: “AI for personalized cancer care”
https://qcb.ucla.edu/wp-content/uploads/sites/14/2025/03/Yala_Adam_Edited-Recording-1.mp4

Frontiers in Computational Biosciences Seminar Series: Brenna Henn, PhD, Associate Professor, Department of Anthropology, Co-Director: Northern Cape Tuberculosis Project - UC Davis
2025-03-31 12:00 - 13:00 | Boyer Hall 159
TITLE: “Why study human genomic diversity in African populations?”

QCBio's New Quarterly Faculty Research Forum
2025-03-18 10:30 - 13:30 | Hershey Hall
We are excited to launch a quarterly QCBio Faculty Research Forum—a new initiative to spark innovation and collaboration, and shape the future of UCLA computational biosciences.
We invite you to join us for the inaugural event on March 18, 2025, from 10:30 AM to 1:30 PM in Hershey Hall Grand Salon.
We have terrific line-up of Faculty speakers:

Chongyuan Luo
Roy Wollman
Jamie Lloyd-Smith
Elisa Franco
Alan Garfinkel

If interested, fill out the registration form. Please make sure you respond by March 10, 2025.

Frontiers in Computational Biosciences Seminar Series: Christian Huber, PhD, Assistant Professor of Biology, Penn State University
2025-03-10 12:00 - 13:00 | Boyer Hall 159

Frontiers in Computational Biosciences Seminar Series: Jianzhi "George" Zhang, PhD, Marshall W. Nirenberg Collegiate Professor, University of Michigan
2025-03-03 12:00 - 13:00 | Boyer Hall 159

Frontiers in Computational Biosciences Seminar Series: Aik Choon Tan, PhD, Senior Director of Data Science, Huntsman Cancer Institute: Jon M. and Karen Huntsman Endowed Chair in Cancer Data Science and Professor, University of Utah
2025-02-24 12:00 - 13:00 | Boyer Hall 159

Computational Pathology Faculty Candidate Presentation - Dr. Matthew Jones
2025-02-20 08:00 - 09:00 | AS-260
Matthew Jones, PhD
Computational Pathology Faculty Candidate
Postdoctoral Fellow, Department of Dermatology, Stanford University School of Medicine
TITLE: “Unraveling The Evolutionary Principles of Cancer”

W11: Metagenomics Analysis with Python and R
2025-02-18 09:00 - 2025-02-20 12:00 | 529 Boyer Hall, 611 Charles E Young Dr E,, Los Angeles, CA, 90095, United States
This workshop provides an introduction to the microbiome analyses from the raw sequence data generated from the next-generation sequencing platforms. We will cover how to perform the 16S rRNA-based analysis using an open-source bioinformatics pipeline QIIME. We will also cover some downstream analyses of the microbiome data beyond QIIME, including statistical analyses and functional analyses.

Frontiers in Computational Biosciences Seminar Series: Karthik Sarma, MD, PhD, Chief Technology Officer, SimX; Computational Medical Scientist and Clinical Psychiatrist, UCSF
2025-02-10 12:00 - 13:00 | Boyer Hall 159

Frontiers in Computational Biosciences Seminar Series: Katie Hoadley, PhD, Associate Professor, Genetics, UNC-Chapel Hill
2025-02-03 12:00 - 13:00 | Boyer Hall 159

Frontiers in Computational Biosciences Seminar Series: Gary Bader, PhD, Professor, The Donnelly Centre, University of Toronto
2025-01-27 12:00 - 13:00 | Boyer Hall 159

Frontiers in Computational Biosciences Seminar Series: Imon Banerjee, PhD, Associate Professor & Consultant, Department of Radiology, Department of Artificial Intelligence & Informatics (AI&I), and Lead AI Scientist, Mayo Clinic Arizona
2025-01-13 12:00 - 13:00 | Boyer Hall 159

Frontiers in Computational Biosciences Seminar Series: Iman Hajirasouliha, PhD., Associate Professor of Computational Genomics in Biomedicine, Weill Cornell Medicine
2025-01-06 12:00 - 13:00 | Boyer Hall 159
TITLE: “Somatic structural variation detection with deep learning and a core modular analysis pipeline“

QCBio 10th Anniversary
2024-12-10 18:00 - 19:30 | Hershey Hall

QCBio 10th Anniversary
2024-12-10 09:00 - 17:00 | Hersey Hall 158
10th Anniversary of the Institute for Quantitative and Computational Biosciences
Welcome Remarks: Tracy Johnson Dean, Life Sciences, UCLA College Professor, Molecular, Cell & Developmental Biology Keith and Cecilia Terasaki Presidential Endowed Chair
Establishing the UCLA Institute for Quantitative & Computational Biosciences: Victoria L. Sork Former Dean, Life Sciences, UCLA College Distinguished Professor, Ecology & Evolutionary Biology
Celebrating 10 Years of Innovation and Discovery moderated by: Alexander Hoffmann Director, Institute for Quantitative and Computational Biosciences Distinguished Professor, Microbiology, Immunology & Molecular Genetics Thomas M. Asher Endowed Chair in Microbiology
Innovation Panelists:

Mehdi Bouhaddou Assistant Professor, Microbiology, Immunology & Molecular Genetics
Eric Deeds Director, Life Science Education Core in Mathematics Professor, Integrative Biology & Physiology
Jamie Lloyd-Smith Professor, Ecology & Evolutionary Biology
Matteo Pellegrini Director, QCBio Collaboratory Chair, Computational & Systems Biology Major Professor, Molecular, Cell & Developmental Biology, Human Genetics
Grace Xiao Director, Computational Biosciences Graduate Programs Professor, Integrative Biology & Physiology
Xia Yang Professor, Integrative Biology & Physiology, Molecular

Frontiers in Computational Biosciences Seminar Series: Stephen Montgomery, PhD, Stanford Medicine Endowed Professor of Pathology and Professor of Genetics, Biomedical Data Science and Computer Science, Stanford University
2024-12-02 12:00 - 13:00 | Boyer Hall 159
TITLE: TBD
Hosted by Brunilda Balliu for Genetics & Genomics

Frontiers in Computational Biosciences Seminar Series: Andrea Ganna, PhD, Associate Professor at FIMM and HiLIFE; Research Associate, Harvard Medical School and Massachusetts General Hospital
2024-11-25 12:00 - 13:00 | Boyer Hall 159
TITLE: TBD
Hosted by Sriram Sankararaman for Bioinformatics

W32: GitHub/Docker
2024-11-19 09:00 - 2024-11-21 12:00 | 529 Boyer Hall, 611 Charles E Young Dr E,, Los Angeles, CA, 90095, United States
Learn how to make your applications ready for production and distribution. This workshop will give you your introduction to setting up version control and containerization for your applications to ensure that changes are tracked and dependencies are documented and automatically installed. Git and Docker allow developers and users to quickly replicate code and computing environments while facilitating collaboration between individuals around the world. Learn how to harness these technologies so you will never again be left saying, “I don’t get it, it worked on my computer.”

Frontiers in Computational Biosciences Seminar Series: Brenna M. Henn, PdD, Associate Professor, Department of Anthropology; Co-Director, Northern Cape Tuberculosis Project, UC Davis
2024-11-18 12:00 - 13:00 | Boyer Hall 159
TITLE: TBD
Hosted by Noah Naitlen for Genetics & Genomics

W7: ChIP-seq Analysis
2024-11-05 13:30 - 2024-11-07 15:30 | 529 Boyer Hall, 611 Charles E Young Dr E,, Los Angeles, CA, 90095, United States
This workshop aims to provide skills needed to address principles of the assay, quality assessment, sequencing depth, data processing and functional downstream analyses of ChIP-seq datasets. Students will have opportunities to practice hands-on with state-of-the-art analytical tools.
