High-throughput sequencing technologies have allowed researchers to extract DNA at the individual, population, and species levels. In this workshop, students will learn how to analyze and interpret population-level genetic information with PLINK and R. Students will also be exposed to the literature on the different topics, followed by hands-on exercises and paper discussion.
TITLE: "Designing synthetic circuits for biological understanding and therapeutic applications"
TITLE: "Inference of the demographic histories and selective effects of human gut commensal microbiota over the course of human history" ABSTRACT: Despite the importance of gut commensal microbiota to human health, there is little knowledge about their evolutionary histories, including their demographic histories and distributions of fitness effects (DFE) of mutations. Here, we infer the […]
TITLE: "Discovering biomarkers for predicting response to neo-adjuvant ADT and radionuclide treatment in high-risk prostate cancer" ABSTRACT: Prostate cancer is the number one cause of cancer death in non-smoking American men. Next generation treatments for prostate cancer include androgen deprivation therapy (ADT) drugs such as Enzalutamide and radionuclide treatments like Lu-PSMA-617. While both of these […]
TITLE: TBD Hosted by Alexander Hoffmann for Bioinformatics
TITLE: “Mechanisms of differences in gene expression and organismal traits caused by structural variation (both real and imagined)” Hosted by Leonid Kruglyak for Genetics & Genomics
TITLE: TBD Hosted by Paul Spellman for Genetics & Genomics
R (www.r-project.org) is a free software environment for statistical computing and graphics. First, this workshop introduces basic concepts, syntax, and usage in R programming, statistical analysis, and visualization techniques. We will conduct hands-on tutorials throughout the session, giving attendees a chance to see R in action. This course is a pre-requisite for several other Collaboratory […]
TITLE: TBD Hosted by Kirk Lohmueller for Bioinformatics
TITLE: Sensing and applying multi-axial tension to biomolecules using molecular devices built from DNA. ABSTRACT: DNA nanotechnology enables the construction of molecular devices for diverse biomedical applications. By leveraging DNA's exquisite positional control, researchers can engineer sophisticated nanostructures that execute a range of tasks. In this talk, I will present 2 DNA-based devices: an amphiphilic […]
