TITLE: "Stochastic Model and Optimization of SELEX." ABSTRACT: Systematic Evolution of Ligands by EXponential enrichment (SELEX) is a process to select the best aptamer sequence in a huge aptamer library […]
TITLE: "Tensor Factorization for Interpreting the Mechanisms of MRSA Persistence." ABSTRACT: Methicillin-resistant Staphylococcus aureus (MRSA) bacteria is an increasingly common and life-threatening infection. While some antibiotics resolve MRSA infections in […]
TITLE: "Baseline MEthylation Patterns prior to flu vaccination." ABSTRACT: Influenza affects millions worldwide each year with responses varying from individual to individual. Influenza can be broken down into subtypes specifically H1N1, […]
TITLE: "Universal annotation of the human genome through integration of over a thousand epigenomic datasets." ABSTRACT: Genome-wide maps of chromatin marks such as histone modifications and open chromatin sites provide […]
TITLE: "Model driven design and analysis of functional screens" ABSTRACT: A little over a decade ago biomedicine was revolutionized by a conceptually simple insight: DNA sequencers could be used as […]
TITLE: "Evolutionary dynamics in the human gut microbiome from infancy through adulthood." ABSTRACT: While the ecological dynamics of the infant gut microbiome have been intensely studied, relatively little is known […]
TITLE: "A lack of distinct cellular identities in scRNA-seq data: revisiting Waddington’s landscape". ABSTRACT: Single-cell RNA sequencing is revolutionizing our understanding of development, differentiation and disease. Analysis of this data is often challenging, however, […]
TITLE: "Swab-Seq: Detecting COVID-19 with Genomic Sequencing: From bench to vending machine." ABSTRACT: At UCLA we developed one of the only novel technologies for COVID-19 diagnostic testing that was deployed […]
TITLE: “Integrative systems analysis, applications, and challenges of single cell multiomics.” ABSTRACT: Recent advances in single cell multiomics technologies such as single cell RNA-seq, single cell ATAC-seq, and spatial transcriptomics […]
TITLE: "Exploration of human genetic and phenotypic diversity through cell villages". ABSTRACT: Our species is characterized by an immense diversity in neurological and psychological traits. Common and rare genetic variants have […]