2017

CRISPR-Mediated VHL Knockout Generates an Improved Model for Metastatic Renal Cell Carcinoma
Authors: Shiruyeh Schokrpur, Junhui Hu, Diana L. Moughon, Peijun Liu, Lucia C. Lin, Kip Hermann, Serghei Mangul, Wei Guan, Matteo Pellegrini, Hua Xu, and Lily Wua
Journal: Scientific Report

Addressing the Digital Divide in Contemporary Biology: Lessons from Teaching UNIX
Authors: Serghei Mangul, Lana S. Martin, Alexander Hoffmann, Matteo Pellegrini, Eleazar Eskin
Journal: Trends in Biotechnology

Targeted mutagenesis in a human-parasitic nematode
Authors: Spencer S. Gang, Michelle L. Castelletto, Astra S. Bryant, Emily Yang, Nicholas Mancuso, Jacqueline B. Lopez, Matteo Pellegrini, Elissa A. Hallem
Journal: PLOS Pathogens

Human embryonic stem cells do not change their X-inactivation status during differentiation
Sanjeet Patel, Giancarlo Bonora, Anna Sahakyan, Rachel Kim, Constantinos Chronis, Justin Langerman, Sorel Fitz-Gibbon, Liudmilla Rubbi, Rhys J.P. Skelton, Reza Ardehali, Matteo Pellegrini, William E. Lowry, Amander T. Clark, Kathrin Plath
Journal: Cell Reports

NOTCH1 is a mechanosensor in adult arteries
Authors: Julia J. Mack, Thiago S. Mosqueiro, Brian J. Archer, William M. Jones, Hannah Sunshine, Guido C. Faas, Anais Briot, Raquel L. Aragón, Trent Su, Milagros C. Romay, Austin I. McDonald, Cheng-Hsiang Kuo, Carlos O. Lizama, Timothy F. Lane, Ann C. Zovein, Yun Fang, Elizabeth J. Tarling, Thomas Q. de Aguiar Vallim, Mohamad Navab, Alan M. Fogelman, Louis S. Bouchard & M. Luisa Iruela-Arispe
Journal: Nature Communications

Genomic divergence across ecological gradients in the Central African rainforest songbird (Andropadus virens)
Authors: Ying Zhen, Ryan J Harrigan, Kristen C Ruegg, Eric C Anderson, Thomas C Ng, Sirena Lao, Kirk E Lohmueller, Thomas B Smith
Journal: Molecular Ecology

An epigenetic aging clock for dogs and wolves
Michael J. Thompson, Bridgett von Holdt, Steve Horvath, Matteo Pellegrini 
Journal: Aging

Distinct Shifts in Microbiota Composition during Drosophila Aging Impair Intestinal Function and Drive Mortality 
Authors: Clark RI, Salazar A, Yamada R3, Fitz-Gibbon S, Morselli M, Alcaraz J, Rana A, Rera M, Pellegrini M, Ja WW, Walker DW.
Journal: Cell Reports

Opposing roles of Toll-like receptor and cytosolic DNA-STING signaling pathways for Staphylococcus aureus cutaneous host defense
Philip O. Scumpia, Giovanni A. Botten , Joshua S. Norman, Kindra M. Kelly-Scumpia, Roberto Spreafico, Amber R. Ruccia, Prabhat K. Purbey, Brandon J. Thomas, Robert L. Modlin, Stephen T. Smale
Journal: PLOS Pathogens

Cbx3 maintains lineage specificity during neural differentiation
Chengyang Huang, Trent Su, Yong Xue, Chen Cheng, Fides D. Lay, Robin A. McKee, Meiyang Li, Ajay Vashisht, James Wohlschlegel, Bennett G. Novitch, Kathrin Plath, Siavash K. Kurdistani and Michael Carey
Journal: Genes & Development

2016

CRISPR/Cas9-Mediated Correction of the Sickle Mutation in Human CD34+ cells
Authors: Megan D Hoban, Dianne Lumaquin, Caroline Y Kuo, Zulema Romero, Joseph Long, Michelle Ho, Courtney S Young, Michelle Mojadidi, Sorel Fitz-Gibbon, Aaron R Cooper, Georgia R Lill, Fabrizia Urbinati, Beatriz Campo-Fernandez, Carmen F Bjurstrom, Matteo Pellegrini, Roger P Hollis, Donald B Kohn
Journal: Molecular Therapy