
This course is designed to take researchers with no genomic experience through variant calling based on the Broad InstituteÕs best practices for GATK. This workshop will be designed to take users from raw sequence data to called variants with emphasis placed on understanding when to apply the best practices or when a particular study or system dictates that you deviate from them. WeÕll emphasize reproducibility of data processing and combining data sets with shell scripts and for-loops to minimize accidental processing errors. By the end of the course, students should feel comfortable working through their own data and have sufficient knowledge to know when and how to deviate from best practices.