TITLE: "ClusterDE: a post-clustering differentially expressed (DE) gene identification method robust to false-positive inflation caused by double-dipping" ABSTRACT: In typical single-cell RNA-seq data analysis, first, a clustering algorithm is applied […]
TITLE: "Germline structural variants shape prostate cancer clinical and molecular evolution." ABSTRACT: Inherited genetic variation profoundly influences cancer risk and outcome. While the impact of germline single nucleotide polymorphisms has […]
The workshop will cover experimental approaches to protein interaction determination; processing and presentation of interaction data available from online resources, and the role of interaction data in the interpretation of large scale datasets. Highly encourage: Students should working knowledge of python scripting.
Join us for an illuminating conversation with: Alexander Hoffmann, Director, Institute for Quantitative & Computational Biosciences, Thomas M. Asher Professor of Microbiology, UCLA Microbiology, Immunology & Molecular Genetics Elaine F. Reed, Daljit S. and Elaine Sarkaria Endowed Chair in Diagnostic Medicine, Professor, Pathology and Laboratory Medicine, Director, UCLA Immunogenetics Center Aaron Meyer, Assistant Professor, Bioengineering With introductory remarks by Tracy […]
TITLE: "FastGxC: a statistical framework for mapping context-specific regulatory variants using bulk and single-cell RNA-seq data." ABSTRACT: Recent studies suggest that context-specific eQTLs underlie genetic risk factors for complex diseases. However, methods for identifying […]
TITLE: "A lack of distinct cellular identities in scRNA-seq data: revisiting Waddington’s landscape." ABSTRACT: Single-cell RNA sequencing is revolutionizing our understanding of development, differentiation and disease. Analysis of this data is often […]
TITLE: "Single Cell Multiomics Integration to Understand Complex Diseases." ABSTRACT: Recent advances in single cell multiomics technologies such as single cell RNA-seq, single cell ATAC-seq, and spatial transcriptomics have brought […]
TITLE: "Liquid Biopsies for Precision Oncology." ABSTRACT: Liquid biopsies are new diagnostic approaches to profile molecular features of solid tumors by blood, saliva, urine, and other body fluids. Such approaches […]
