TITLE: "Tensor Factorization for Interpreting the Mechanisms of MRSA Persistence." ABSTRACT: Methicillin-resistant Staphylococcus aureus (MRSA) bacteria is an increasingly common and life-threatening infection. While some antibiotics resolve MRSA infections in vitro, these same antibiotics often fail to clear an infection when used to treat patients, suggesting that MRSA persistence is a confluence of both host […]
TITLE: "Baseline MEthylation Patterns prior to flu vaccination." ABSTRACT: Influenza affects millions worldwide each year with responses varying from individual to individual. Influenza can be broken down into subtypes specifically H1N1, H3N2, Yamagata, and Victoria. One way to measure the immune response to influenza is to measure a person’s antibody response to influenza. To measure how […]
TITLE: "Universal annotation of the human genome through integration of over a thousand epigenomic datasets." ABSTRACT: Genome-wide maps of chromatin marks such as histone modifications and open chromatin sites provide valuable information for annotating the non-coding genome, including identifying regulatory elements. Computational approaches such as ChromHMM have been applied to discover and annotate chromatin states […]
TITLE: "Model driven design and analysis of functional screens" ABSTRACT: A little over a decade ago biomedicine was revolutionized by a conceptually simple insight: DNA sequencers could be used as […]
TITLE: "Evolutionary dynamics in the human gut microbiome from infancy through adulthood." ABSTRACT: While the ecological dynamics of the infant gut microbiome have been intensely studied, relatively little is known […]
TITLE: "A lack of distinct cellular identities in scRNA-seq data: revisiting Waddington’s landscape". ABSTRACT: Single-cell RNA sequencing is revolutionizing our understanding of development, differentiation and disease. Analysis of this data is often challenging, however, […]
TITLE: "Swab-Seq: Detecting COVID-19 with Genomic Sequencing: From bench to vending machine." ABSTRACT: At UCLA we developed one of the only novel technologies for COVID-19 diagnostic testing that was deployed […]
TITLE: “Integrative systems analysis, applications, and challenges of single cell multiomics.” ABSTRACT: Recent advances in single cell multiomics technologies such as single cell RNA-seq, single cell ATAC-seq, and spatial transcriptomics […]
TITLE: "Exploration of human genetic and phenotypic diversity through cell villages". ABSTRACT: Our species is characterized by an immense diversity in neurological and psychological traits. Common and rare genetic variants have […]
The workshop introduces Cytoscape (https://cytoscape.org/) – an open source platform for retrieval and visualization of complex biological interactions that are available from public interaction resources: The IMEx Consortium (https://www.imexconsortium.org/), STRING […]
