TITLE: "Universal annotation of the human genome through integration of over a thousand epigenomic datasets." ABSTRACT: Genome-wide maps of chromatin marks such as histone modifications and open chromatin sites provide valuable information for annotating the non-coding genome, including identifying regulatory elements. Computational approaches such as ChromHMM have been applied to discover and annotate chromatin states […]

TITLE: "Model driven design and analysis of functional screens" ABSTRACT: A little over a decade ago biomedicine was revolutionized by a conceptually simple insight: DNA sequencers could be used as […]

TITLE: "Evolutionary dynamics in the human gut microbiome from infancy through adulthood." ABSTRACT: While the ecological dynamics of the infant gut microbiome have been intensely studied, relatively little is known […]

TITLE: "A lack of distinct cellular identities in scRNA-seq data: revisiting Waddington’s landscape". ABSTRACT: Single-cell RNA sequencing is revolutionizing our understanding of development, differentiation and disease. Analysis of this data is often challenging, however, […]

TITLE: "Swab-Seq: Detecting COVID-19 with Genomic Sequencing: From bench to vending machine." ABSTRACT: At UCLA we developed one of the only novel technologies for COVID-19 diagnostic testing that was deployed […]

TITLE: “Integrative systems analysis, applications, and challenges of single cell multiomics.” ABSTRACT: Recent advances in single cell multiomics technologies such as single cell RNA-seq, single cell ATAC-seq, and spatial transcriptomics […]

TITLE: "Predicting Biological Aging from Epigenetics." ABSTRACT: Epigenetics are a proven measure of cellular health. Therefore, a field of research has emerged that utilizes epigenetics to measure, treat, and potentially […]