"MsCAVIAR: Identifying Causal Variants by Fine Mapping Across Multiple Studies"

TITLE: "Chemical reactions and condensates" ABSTRACT: In the past decade, condensates have been implicated as a mechanism of organization in biological systems. In addition to the potentially biologically relevant aspects of […]

TITLE: "Merging Experimental and Computational Approaches to Study Neurodegenerative Disease Dynamics" ABSTRACT: Neurodegenerative diseases such as Alzheimer's and Parkinson's affect millions of people around the world and are a growing […]

TITLE: "Symmetry breaking during morphogenesis of a mechanosensory organ" ABSTRACT: The development of mechanosensory epithelia, such as those of the auditory and vestibular systems, results in the precise orientation of mechanosensory […]

TITLE: "Biologist, Know Thy Cells - A Colorful Barcoding Method to ID Cell Types, their Fate, and Decode Brainwide Communication" ABSTRACT: A major challenge in biological imaging is resolving cell identities. […]

TITLE: "Enhancer Loss and Gene Dosage Sensitivity Drives a Human Craniofacial Disorder" ABSTRACT: In recent years, the importance of understanding the role of non-coding regulatory mutations in human disease has become […]

TITLE: “Merging Experimental and Computational Approaches to Study Neurodegenerative Disease Dynamics” ABSTRACT: "Neurodegenerative diseases such as Alzheimer's and Parkinson's affect millions of people around the world and are a growing health concern […]

TITLE: "A quantitative view of strategies to engineer cell-selective ligand binding" ABSTRACT: Selective binding to specific target cells is a critical property of many therapies. To enhance selectivity in specific situations, a series of new strategies have been proposed in the drug development literature, including affinity, valency, multi-specificity, and other alterations to target cell binding. […]

TITLE: "Organoid Maturation by Circadian Entrainment " ABSTRACT: Stem cell-derived tissues that recap endogenous physiology are key for regenerative medicine. Yet, most methods yield products that function like fetal, not adult tissues. Organoids are typically grown in constant environments, while our tissues mature along with behavioral cycles. I show that inducing circadian rhythms in pancreatic islet organoids, […]

TITLE: "Building an integrated framework for tissue morphogenesis with the zebrafish inner ear" ABSTRACT: How simple tissues give rise to geometrically complex organs with robust shapes and functions is a fundamental question in biology with important implications in disease and translational medicine. The current mechanistic framework explains how upstream genetic and biochemical information pattern cellular mechanics […]