Bioinformatics/Human Genetics Seminar Series: Jason Moore, PhD, Founding Chair of the Department of Computational Biomedicine, Cedars-Sinai
TITLE: "Automated genetic analysis" Hosted by Nandita Garud.
TITLE: "Automated genetic analysis" Hosted by Nandita Garud.
TITLE: "Genomics for precision public health in Colombia" Hosted by Juan De La Hoz.
https://socalsysbio.qcb.ucla.edu
Phylogenetics – the reconstruction of the evolutionary history of a the variety of species known to us, is among the most fundamental and traditional tasks in Biology. With the dramatic […]
TITLE: "G-Flux: a metabolic flux and free energy analysis software for interpreting 13C, 2H, 18O, and 15N isotope tracing data." ABSTRACT: Metabolic fluxes offer insights into pathway utilization, kinetics, and […]
TITLE: "PCA outperforms popular hidden variable inference methods for QTL mapping." ABSTRACT: Estimating and accounting for hidden variables is widely practiced as an important step in quantitative trait locus (QTL) […]
TITLE: "Stochastic Model and Optimization of SELEX." ABSTRACT: Systematic Evolution of Ligands by EXponential enrichment (SELEX) is a process to select the best aptamer sequence in a huge aptamer library […]
TITLE: "Tensor Factorization for Interpreting the Mechanisms of MRSA Persistence." ABSTRACT: Methicillin-resistant Staphylococcus aureus (MRSA) bacteria is an increasingly common and life-threatening infection. While some antibiotics resolve MRSA infections in vitro, these same antibiotics often fail to clear an infection when used to treat patients, suggesting that MRSA persistence is a confluence of both host […]
TITLE: "Baseline MEthylation Patterns prior to flu vaccination." ABSTRACT: Influenza affects millions worldwide each year with responses varying from individual to individual. Influenza can be broken down into subtypes specifically H1N1, H3N2, Yamagata, and Victoria. One way to measure the immune response to influenza is to measure a person’s antibody response to influenza. To measure how […]
TITLE: "Universal annotation of the human genome through integration of over a thousand epigenomic datasets." ABSTRACT: Genome-wide maps of chromatin marks such as histone modifications and open chromatin sites provide valuable information for annotating the non-coding genome, including identifying regulatory elements. Computational approaches such as ChromHMM have been applied to discover and annotate chromatin states […]