TITLE: "Heterogeneity in cell states: Is it important whether cell states are heritable or change rapidly?" ABSTRACT: Cells of the same cell type show molecular and phenotypic heterogeneity. Is the particular cell state of a given cell heritable from one generation to the next?  Previous work in liver cancer cells indicates that the molecular network […]

TITLE: "scReadSim: a single-cell RNA-seq and ATAC-seq read simulator." ABSTRACT: Rapid advances of single-cell RNA-seq and ATAC-seq technologies have propelled the development of many computational tools, benchmarking of which demands realistic simulators. However, few simulators can generate sequencing reads, and none of the existing read simulators aim to mimic real cells, hindering the benchmarking of […]