QCBio/Center for Biological Physics: Gregoire Altan-Bonnet, Principal Investigator – Immunodynamics group Laboratory of Integrative Cancer Immunology NCI, NIH, Bethesda MD
TITLE: “Stochasticity in cancer immunotherapies: identifying the T cell subset that sparks tumor eradication” ABSTRACT: We use an ex vivo model of tumor eradication to dissect the fundamental variability of clinical outcomes in cancer immunotherapies. We demonstrate that there exists an inherent stochastic variability in immune responses, based on the low abundance of hyper-responsive naïve T cells (so-called […]
