“A lack of distinct cellular identities in scRNA-seq data: revisiting Waddington’s landscape” Single-cell RNA sequencing is revolutionizing our understanding of development, differentiation and disease. Analysis of this data is often challenging, however, and tasks like clustering cells to uncover distinct cellular identities sometimes yields results that fail to align with existing biological knowledge. We analyzed […]

“Unraveling Signaling Pathway Crosstalk Using LLMs” Living cells do not process information through isolated, linear pathways. Instead, they rely on an intricate network of signaling crosstalk to make critical fate decisions. Deciphering this hidden cellular conversation remains one of the greatest challenges in targeted oncology and regenerative medicine. Yet traditional mechanistic models struggle to capture […]

TITLE: "Evolutionary perspectives on malaria" Pathogen genomics increasingly guides public health decisions, yet organisms with complex life cycles can produce genealogies that violate assumptions of standard population genetic methods. Similarly, […]