Bioinformatics/Human Genetics Seminar Series: Dana Pe’er, PhD, Chair, Computational and Systems Biology Program, Sloan Kettering Institute
TITLE: "Cellular plasticity in Cancer." Hosted by Jason Ernst.
TITLE: "Cellular plasticity in Cancer." Hosted by Jason Ernst.
TITLE: "Characterizing distinct cell states based on stimulus-response dynamics." ABSTRACT: Macrophages show remarkable functional pleiotropy that is dependent on microenvironmental context. Prior studies have characterized how polarizing cytokines alter epigenetic […]
TITLE: "Quantitative flux analysis reveals redistribution of glycolytic pathways in dynamic nutrient environments." ABSTRACT: Optimal operation of metabolic fluxes is critical for an organism to be evolutionarily competitive. Textbook glycolysis […]
TITLE: “Walking the line between progress and paternalism in genetic counseling.” Hosted by Christina Palmer.
TITLE: "Multimodal Single-Cell Epigenomic Sequencing of the Developing Human Cerebral Cortex." ABSTRACT: Single cell epigenomic technologies allow the measurement of unique molecular signatures within cells, however cell type complexity remains highly […]
TITLE: "moPepGen: a fast custom database generator from multi-omics data for proteogenomics." ABSTRACT: Cancers are driven by genomic variants such as SNV (single nucleotide variants) and INDEL, often accompanied by […]
TITLE: "Automated genetic analysis" Hosted by Nandita Garud.
TITLE: "Genomics for precision public health in Colombia" Hosted by Juan De La Hoz.
TITLE: "G-Flux: a metabolic flux and free energy analysis software for interpreting 13C, 2H, 18O, and 15N isotope tracing data." ABSTRACT: Metabolic fluxes offer insights into pathway utilization, kinetics, and […]
TITLE: "PCA outperforms popular hidden variable inference methods for QTL mapping." ABSTRACT: Estimating and accounting for hidden variables is widely practiced as an important step in quantitative trait locus (QTL) […]