Frontiers in Computational Biosciences Seminar Series: Monica Munoz-Torres, PhD, Associate Professor, Department of Biomedical Informatics, University of Arizona
TITLE: "TBD" Hosted by William Hsu for Medical Informatics
TITLE: "TBD" Hosted by William Hsu for Medical Informatics
TITLE: "Splicing-specific transcriptome-wide association uncovers novel genetic mechanisms for Schizophrenia." ABSTRACT: Recent studies have highlighted the essential role of RNA splicing, a key mechanism of alternative RNA processing, in establishing connections between genetic variations and disease. Genetic loci influencing RNA splicing variations show considerable influence on complex traits, possibly surpassing those affecting total gene expression. Dysregulated RNA […]
TITLE: "Modeling the heterogenous NFκB dynamics of single immune cells." ABSTRACT: Macrophages function as immune sentinel cells, initiating appropriate and specialized immune responses to a great variety of pathogens. The transcription factor NFκB controls macrophage gene expression responses, and its temporal dynamics enable stimulus-specificity of these responses. Using a fluorescent reporter mouse our laboratory recently […]
TITLE: "The new culture of preprint peer-review"
TITLE: "TBD" Hosted by Grace Xiao for Bioinformatics
TITLE: "Characterization of Genomics Landscape and Natural History of Anaplastic Thyroid Cancer using High Depth WGS and Subclonal Reconstruction." ABSTRACT: Anaplastic thyroid cancer (ATC) is among the most lethal cancer […]
TITLE: "scGRNdb: A Cell Type Gene Regulatory Network Atlas for Human and Mouse." ABSTRACT: Gene regulatory networks (GRNs) elucidate the complex regulatory landscape in cells and tissues, making them powerful tools […]
TITLE: "TBD" Hosted by Jingyi Jessica Li for Bioinformatics
TITLE: "A Non-Invasive Epigenetic Measure of Inflammation." ABSTRACT: Existing epigenetic phenotype tests often lack mechanistic explanations of the observed correlations between specific methylation sites and phenotypes. This raises the crucial […]
TITLE: "scDEED: a statistical method for detecting dubious 2D single-cell embeddings and optimizing t-SNE and UMAP hyperparameters." ABSTRACT: Two-dimensional (2D) embedding methods are crucial for single-cell data visualization. Popular methods […]