Friday Jun, 04, 2021 - 11:30 AM

QCBio Research Seminar: Nan (Miles) Xi (Li JJ)

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TITLE: “DoubletCollection: An R package that integrates cutting-edge computational doublet-detection methods.” ABSTRACT: The existence of doublets is a key confounder in single-cell RNA sequencing (scRNA-seq) data analysis. There are several …

Friday Jun, 04, 2021 - 11:00 AM

QCBio Research Seminar: Amelia Palermo (Graeber)

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TITLE: “Metabolic dependencies of ecDNA and HSR focal amplification modes and plasticity.” ABSTRACT: The focal amplification (FA) of genes that support the uncontrolled growth and proliferation of cells (i.e., oncogenes) …

Friday May, 28, 2021 - 11:00 AM

QCBio Research Seminar: Yi Ding (Pasaniuc)

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TITLE: “Large uncertainty in individual PRS estimation impacts PRS-based risk stratification.” ABSTRACT: Large-scale genome-wide association studies have enabled polygenic risk scores (PRS), which estimate the genetic value of an individual …

Friday May, 28, 2021 - 11:00 AM

QCBio Research Seminar: Jakob Von Morgenland (Venugopal)

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TITLE: “Constructing a Functional Interactome from Published Work to Identify Underrepresented and Integrative Effects of Neuroinflammatory Cytokines on Neural Excitability.” ABSTRACT: Maintaining normal excitability is a key function of our …

Friday May, 21, 2021 - 11:30 AM

QCBio Research Seminar: Shamus Cooley (Deeds)

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TITLE: “Unbiased analysis of single cell RNA sequencing data reveals previously uncharacterized heterogeneity in small cell lung cancer cell lines.” ABSTRACT: Small Cell Lung Cancer (SCLC) accounts for approximately 13% …

Friday May, 21, 2021 - 11:00 AM

QCBio Research Seminar: Olga Schubert (Kruglyak)

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TITLE: “Genome-wide survey of mutations influencing protein abundances in yeast” ABSTRACT: Our understanding of how protein-level regulation is encoded in the genome and how protein abundances are affected by DNA …