TITLE: “The new forensic genetics: 'long-range' search and genetic privacy.” Hosted by Nandita Garud.
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TITLE: “The new forensic genetics: 'long-range' search and genetic privacy.” Hosted by Nandita Garud. |
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TITLE: "P-value-free solution to fix exaggerated false positives by popular differential expression methods." ABSTRACT: We report a surprising phenomenon that popular bioinformatics methods for identifying differentially expressed genes (DEG) between two conditions have unexpectedly high false discovery rates (FDRs) on large-sample-size RNA-seq datasets. Failed FDR control is likely due to the invalid p-values which rely on […] |
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TITLE: "Cellular plasticity in Cancer." Hosted by Jason Ernst. |
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TITLE: "Characterizing distinct cell states based on stimulus-response dynamics." ABSTRACT: Macrophages show remarkable functional pleiotropy that is dependent on microenvironmental context. Prior studies have characterized how polarizing cytokines alter epigenetic […]
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TITLE: "Quantitative flux analysis reveals redistribution of glycolytic pathways in dynamic nutrient environments." ABSTRACT: Optimal operation of metabolic fluxes is critical for an organism to be evolutionarily competitive. Textbook glycolysis […] |
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TITLE: “Walking the line between progress and paternalism in genetic counseling.” Hosted by Christina Palmer. |
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TITLE: "Multimodal Single-Cell Epigenomic Sequencing of the Developing Human Cerebral Cortex." ABSTRACT: Single cell epigenomic technologies allow the measurement of unique molecular signatures within cells, however cell type complexity remains highly […]
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TITLE: "moPepGen: a fast custom database generator from multi-omics data for proteogenomics." ABSTRACT: Cancers are driven by genomic variants such as SNV (single nucleotide variants) and INDEL, often accompanied by […] |
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TITLE: "Automated genetic analysis" Hosted by Nandita Garud. |
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