TITLE: "Asymptotic-Numerical Method For Cell Focusing in Microfluidic Channel." ABSTRACT: Inertial microfluidic devices use inertial lift forces to organize the spacing and positions of cells carried by flow. A hybrid asymptotic-numerical method is presented that can calculate the migration velocities of cells in a channel by representing them as a combination singularities and discontinuities. Refinements […]
TITLE: "Efficient variance components analysis across millions of genomes." ABSTRACT: While variance components analysis has emerged as a powerful tool in complex trait genetics, existing methods for fitting variance components do not scale well to large-scale datasets of genetic variation. I will present a method for variance components analysis that is accurate and efficient: capable of […]
TITLE: "Quantifying response-specificity to diverse immune threats from single cell transcriptomes" ABSTRACT: Innate immune sentinel cells such as macrophages upregulate over a thousand genes in the minutes to hours following an encounter with pathogen invaders or damage signals. Previous bulk transcriptomic studies suggest there is stimulus-specificity in the combinations of genes that are activated. However, bulk […]
