Friday Jan, 22, 2021 - 11:30 AM
QCBio Research Seminar: Iris Dror (Plath)
TITLE: “XIST controls X chromosome dampening and autosomal genes in early human development” ABSTRACT: Female human pre-implantation embryos and naïve human pluripotent stem cells (hPSCs) equalize X-linked gene expression with males …
Friday Jan, 22, 2021 - 11:00 AM
QCBio Research Seminar: Tevfik Umut Dincer (Ernst)
TITLE: “Genomewide supervised prediction of activating and repressive regions in over hundred cell and tissue types” ABSTRACT: While the vast majority of variants associated with common disease risk are distributed …
Thursday Jan, 21, 2021 - 1:00 PM
Developmental Systems Biology Faculty Search – MCDB | QCBio | BSCRC Seminar: Amjad Askary, PhD, California Institute of Technology, Pasadena, CA
TITLE: “Imaging-based genetic recording of developmental histories” ABSTRACT: Systems-level understanding of cell fate decisions has been hampered by limitations of the existing methods to capture developmental history of the cells. Synthetic …
Thursday Jan, 21, 2021 - 10:00 AM
Developmental Systems Biology Faculty Search – MCDB | QCBio | BSCRC Seminar: Michael F. Wells, PhD, Broad Institute & Harvard University, Cambridge, MA
TITLE: “Exploration of human genetic and phenotypic diversity through cell villages” ABSTRACT: Our species is characterized by an immense diversity in neurological and psychological traits. Common and rare genetic variants have …
Wednesday Jan, 20, 2021 - 11:00 AM
Developmental Systems Biology Faculty Search – MCDB | QCBio | BSCRC Seminar: Yogesh Goyal, PhD, University of Pennsylvania, Philadelphia, PA
TITLE: “Cellular plasticity and fate choices in developing tissues and single cancer cells” ABSTRACT: While cellular processes are often reproducible and precise, cells may also alter their molecular states and adopt …
Tuesday Jan, 19, 2021 - 12:00 PM
Developmental Systems Biology Faculty Search – MCDB | QCBio | BSCRC Seminar: Charlene Guillot (Ryan), PhD, Harvard Medical School, Boston, MA
TITLE: “Understanding how environmental cues regulate Neuro-Mesodermal progenitor cells in development and disease” ABSTRACT: The trunk and tail of vertebrates arise from the addition of mesodermal (i.e., muscle and vertebrae) and …
Tuesday Jan, 19, 2021 - 10:00 AM
Developmental Systems Biology Faculty Search – MCDB | QCBio | BSCRC Seminar: Akankshi Munjal, PhD, Harvard Medical School, Boston, MA
TITLE: “Building an integrated framework for tissue morphogenesis with the zebrafish inner ear” ABSTRACT: How simple tissues give rise to geometrically complex organs with robust shapes and functions is a fundamental …
Friday Jan, 15, 2021 - 12:00 PM
Developmental Systems Biology Faculty Search – MCDB | QCBio | BSCRC Seminar: Juan Alvarez, PhD, Harvard University, Cambridge, MA
TITLE: “Organoid Maturation by Circadian Entrainment ” ABSTRACT: Stem cell-derived tissues that recap endogenous physiology are key for regenerative medicine. Yet, most methods yield products that function like fetal, not adult tissues. …
Friday Jan, 15, 2021 - 11:30 AM
QCBio Research Seminar: Cyrillus Tan (Meyer)
TITLE: “A quantitative view of strategies to engineer cell-selective ligand binding” ABSTRACT: Selective binding to specific target cells is a critical property of many therapies. To enhance selectivity in specific …
Friday Jan, 15, 2021 - 11:00 AM
QCBio Research Seminar: Sharmila Venugopal (Part II)
TITLE: “Merging Experimental and Computational Approaches to Study Neurodegenerative Disease Dynamics” ABSTRACT: “Neurodegenerative diseases such as Alzheimer’s and Parkinson’s affect millions of people around the world and are a growing health concern …
