TITLE: "Distal mediator-enriched placental transcriptome-wide association studies reveal genetic mechanisms supporting the  Developmental Origins of Health and Disease." ABSTRACT: As the master regulator of the intrauterine environment, the placenta is […]

TITLE: "Clipper: p-value-free FDR control on high-throughput data from two conditions." ABSTRACT: High-throughput biological data analysis commonly involves identifying "interesting" features (e.g., genes, genomic regions, and proteins), whose values differ […]

Associate Professor, UCLA Institute for Society and Genetics “TBD” Hosted by Paivi Pajukanta

TITLE: "Critical slowing down signals quasi-species extinction in an evolutionary model with environmental heterogeneity." ABSTRACT: Environmental heterogeneity can significantly affect the evolutionary dynamics of a population. A key parameter that determines the influence of heterogeneity is the migration rate--the rate at which organisms explore their heterogeneous environment. We study a model of a population which migrates between […]

TITLE: "Integrating metabolomics and fluxomics to study cancer metabolism in low glucose environments." ABSTRACT: Metabolomics and fluxomics are integral tools for quantitative metabolic analysis. By combining mass spectrometry, isotope tracing, and mathematical modeling, we can quantify metabolite concentrations and fluxes in cancer cells. Using these tools, we are investigating the coordination of bioenergetics, biosynthesis, and redox […]

Associate Professor, Department of Biochemistry and Biophysics, UCSF “TBD” Hosted by David Eisenberg

TITLE:“Longitudinal phenotyping of Severe Mental Illness from Electronic Health Records.” ABSTRACT:Electronic Health Records (EHRs) offer an exciting avenue for large-scale genetic studies of psychiatric disorders in globally diverse populations. As […]

TITLE: "Population structure inference for biobank-scale data." ABSTRACT: Inferring the structure of human populations from genetic variation data is a key task in population and medical genomic studies. While a […]