Director

Matteo Pellegrini

Matteo Pellegrini

Director

Director Matteo Pellegrini is a biophysicist who has served on the UCLA Life Sciences Division faculty since he joined the Department of Molecular, Cell and Developmental Biology in 2005. Dr. Pellegrini earned his B.A. in Physics at Columbia University and his Ph.D. in Physics at Stanford. He was a postdoctoral fellow at UCLA, where he worked on computational biology. Following his postdoctoral studies Dr. Pellegrini co-founded a start-up company and later worked for the pharmaceutical company Merck before returning to UCLA. His laboratory research centers on the development of novel computational approaches to reverse engineer biomolecular networks. Professor Pellegrini is also a member of the California NanoSystems Institute (CNSI). Email: matteop@mcdb.ucla.edu + Website: https://www.pellegrini.mcdb.ucla.edu/people/

Support Staff

Lana Martin

Lana Martin

Programs Manager

Lana has extensive experience in organizing academic programs and events, and has worked as a Project Manager for ZarLab in the Departments of Computer Science and Human Genetics at UCLA, has organized the UCLA Computational Genetics Summer Institute, and has served as Academic Policy Coordinator at UCLA Graduate Division. Lana has a PhD in Anthropology (subfield: Archaeology) from UCLA. Email: lana.martin@lifesci.ucla.edu

Current Fellows

Alex Brummer

Alex Brummer

Collaboratory Fellow

Dr. Alex Brummer is a postdoctoral scholar in Dr. Van Savage’s group through the Depts. of Biomathematics and of Ecology and Evolutionary Biology. Alex is working with the lab software Angicart to digitally reconstruct and analyze vascular tissues from medical images spanning multiple modalities (e.g. MRI, CT, and micro-CT) to search for geometric signatures of disease and recovery. Concurrent with this, Alex is developing and testing new models for asymmetric branching in vascular networks that relate the degree or pattern of asymmetry to biological scaling exponents that encapsulate how metabolic rate, heart rate, and lifespan change with body size across species. Alex earned B.S. degrees in physics and mathematics at Oregon State University, and his M.S. and Ph.D. degrees in physics at the University of Arizona. Email: abrummer@ucla.edu

Rob Foreman

Rob Foreman

Collaboratory Fellow

Dr. Rob Foreman is a postdoctoral scholar in the lab of Dr. Roy Wollman, Department of Chemistry and Biochemistry. Rob is developing a multiplexed smFISH measurement technique. He wants to use this technique to observe how cells are distributed in a joint gene expression state-space in order to pose questions about these distributions. Email: rforeman@ucla.edu

Karolina Kaczor-Urbanowicz

Karolina Kaczor-Urbanowicz

Collaboratory Fellow

Dr. Karolina E. Kaczor-Urbanowicz, DMD, Phd, MSc is an Assistant Project Scientist in Prof. David Wong’s laboratory of UCLA Center for Oral/Head & Neck Oncology Research and Salivary Diagnostics, Section of Oral Biology, UCLA School of Dentistry. She is a dentist-scientist who graduated from the Faculty of Dental Medicine at the Medical University of Warsaw, Poland. She did her residency in orthodontics simultaneously with the international studies in Bio-Medical Sciences at the Hebrew University of Jerusalem, Israel, working in the Prof. Aaron Palmon’s Laboratory of Proteomics and Salivary Diagnostics, Institute of Dental Sciences. After earning her Ph.D. title, she was awarded the UCLA’s R90 NIH/NIDCR Postdoctoral Dentist-Scientist Scholarship and AACR-DDF postdoctoral fellowship in developing salivary H.pylori exRNA biomarkers for early detection of gastric cancer. At the UCLA, she developed her immense interests in salivary RNA Sequencing, bioinformatics and biomarker development for many oral and systematic diseases including cancer. Email: kkaczor@ucla.edu

Igor Mandric

Igor Mandric

Collaboratory Fellow

Dr. Igor Mandric is currently a postdoctoral fellow in the labs of Bogdan Pasaniuc and Eran Halperin at UCLA. He completed his M.S in Applied Mathematics at Moldova State University. Before joining UCLA, he earned Ph.D in Bioinformatics under the supervision of Alex Zelikovsky at Georgia State University. His main research interest lays in the area of single-cell RNA sequencing. In particular, he is interested in inferring cell-type specific expression profiles in the settings of low sequencing coverage. Additionally, Igor is also interested in statistical fine-mapping for large-scale genotype-phenotype data. Email: imandric@ucla.edu

Marco Morselli

Marco Morselli

Collaboratory Fellow

Dr. Marco Morselli is currently a post-doc in the Lab of Professor Matteo Pellegrini. He received his bachelor and master degrees in Molecular Biotechnology at the University of Parma, Italy. He earned his PhD at UCLA focusing on the crosstalk between histone modifications and DNA methylation. Outside of the lab, Marco enjoys cooking, running, cycling and playing soccer. Email: mmorselli@g.ucla.edu

Alon Oyler-Yaniv

Alon Oyler-Yaniv

Collaboratory Fellow

Dr. Alon Oyler-Yaniv Alon is a postdoctoral researcher in the lab of Dr. Roy Wollman. Alon earned his BS.c., M.Sc., and Ph.D. in Physics from Ben-Gurion University of the Negev. Alon is interested in the effects of the spatial structure of living tissue on cell to cell communication. Using advanced optical tools to image molecular interactions, he studies how cells move and communicate during the process of wound healing in living organs. Email: alonyan@ucla.edu

Nicolas Rochette

Nicolas Rochette

Collaboratory Fellow

Dr. Nicolas C. Rochette is a postdoc in the laboratory of Dr. Shane Campbell-Staton in the Department of Ecology and Evolutionary Biology and the Institute for Society and Genetics. His research intersects population genomics and evolutionary physiology, with the goal of understanding the dynamics of adaptation in quantitative traits. His current projects include work on the genetic architecture of high-altitude adaptation in the North American Deer Mouse, and local adaptation in Caribbean Anole lizards. He was previously a postdoc in the laboratory of Dr. Julian Catchen at the University of Illinois, developing new analytical tools for RADseq data and population genomics in non-model organisms. He received his PhD in Comparative Genomics and MS in Evolutionary Genomics from the University of Lyon and Ecole Normale Superieure de Lyon, in France. Email: nrochette@ucla.edu

Peter Scott

Peter Scott

Collaboratory Fellow

Dr. Peter Scott is a postdoctoral researcher in the laboratory of Dr. Brad Shaffer. He received his PhD in Ecology and Evolutionary Biology from the University of Alabama. Peter’s primary research interests lie in applying genomic methods to understand species limits and diversification, hybrid zone dynamics, and landscape and conservation genomics in reptiles and amphibians. Additionally, he is interested in investigating how to best apply and adapt modern genomic methods to non-model systems that are representative of difficult evolutionary questions (e.g. resolving relationships in recent, rapid radiations), or that push the limits of these technologies (e.g. organisms with very large genomes). Email: pscott17@ucla.edu

Baochen Shi

Baochen Shi

Collaboratory Fellow

Baochen Shi is a postdoc working with Dr. Huiying Li in the department of Molecular and Medical Pharmacology. By studying genomes and transcriptomes of the microorganisms living inside and on the humans, he aims to understand how human microbiome play a role in health and disease. Prior to joining UCLA, he completed his Ph.D. in the bioinformatics lab of Prof. Runsheng Chen in the Institute of Biophysics, Chinese Academy of Sciences. Email: biosbc@ucla.edu

Ying Tang

Ying Tang

Collaboratory Fellow

Dr. Ying Tang is a postdoc in signaling systems laboratory working with Professor Alexander Hoffmann. His research interest is to develop quantitative understanding on immune systems through mathematical modeling, from the level of intracellular information transmission to cell population dynamics. Prior to joining UCLA, he did PhD study in Shanghai Jiao Tong University and University of California, San Deigo. During PhD, he worked on stochastic process, nonequilibrium statistical physics, and mathematical modeling of E. coli chemotaxis. Email: jamestang23@ucla.edu

Anela Tosevska

Anela Tosevska

Collaboratory Fellow

Dr. Anela Tosevska is currently a postdoctoral fellow in the lab of Dr. Matteo Pellegrini at UCLA. She completed her master degree in Pharmacy at Ss. Cyril and Methodius University of Skopje. Before joining UCLA, she earned a PhD in Life Sciences from the University of Vienna, working as a part of the research platform Active Aging. Dr. Tosevska is interested in the role of DNA methylation in aging and age-associated disease progression. She is also working with circulating cell-free nucleic acids from liquid biopsies, trying to understand their function and diagnostic potential in health and disease. Email: atosevska@ucla.edu

Don Vaughn

Don Vaughn

Collaboratory Fellow

Dr. Don Vaughn is a neuroscience postdoctoral fellow at UCLA. His research has included functional Magnetic Resonance Imaging (fMRI), perceptual psychophysics, and sensory substitution. Don uses fMRI to research neural correlates of freewill and how social dynamics modulate empathy. In psychophysics, Don investigated how information, before and after an event has occurred, influences perception of the event - an effect dubbed peri-diction. Don now applies multivariate classification and non-parametric statistics to bioinformatics datasets. Email: donaldavaughn@gmail.com

Michael Weinstein, Ph.D.

Michael Weinstein, Ph.D.

Guest Collaboratory Instructor

Current Position: Scientist, Zymo Research

Weihong Yan

Weihong Yan

Galaxy Administrator

Dr. Weihong Yan is the system administrator of Galaxy. She constructs and maintains software and hardware needed for bioinformatics application. Dr. Wang provides consultation services on microarray, proteomic and genomic data analysis. Email: wyan@chem.ucla.edu

Nathan Zemke

Nathan Zemke

Collaboratory Fellow

Dr. Nathan Zemke is currently a post-doc in the Lab of Professor Arnie Berk in the Microbiology, Immunology, & Molecular Genetics department at UCLA. He received his bachelor’s degree in molecular biology at UCSD. He earned his PhD from the Molecular Biology Interdepartmental program at UCLA researching the adenovirus oncoprotein e1a and its regulation of chromatin, innate immune responses, and differentiation. Email: nzemke@ucla.edu

 

Alumni

Trent Su

Trent Su

Trent Su is a postdoctoral fellow at Dr. Siavash Kurdistani lab in the Department of Biological Chemistry. In collaboration with Dr. Arnie Berk lab, his research focus on using high-throughput genomics methods to study genome-wide epigenetic changes induced by Adenoviral oncoprotein e1a which upon expression forces stationary host cells into S phase. Dr. Su received his B.S. in Molecular and Cell Biology at UC Berkeley. Afterwards, he received his M.S. in Computer Science at UC Irvine where he co-written a java web application for Systems Biology pathway modeling. He completed his PhD training in the Kurdistani lab and received his PhD in Oral Biology at UCLA School of Dentistry. His current interests include writing custom python scripts for high-throughput sequencing analysis and mining cancer mutation databases. Email: ytsu@ucla.edu

Michael Thompson

Michael Thompson

Dr. Michael Thompson received a BA in physics from Boston University, a PhD in biophysics from the University of Michigan. Over his research career, Michael has invented quantitative methods for predicting protein structure from evolutionary information, prion proteins from sequence determinants, and gene function from co-evolution. Michael is currently working with Prof. Pellegrini and Prof. Horvath to illuminate the role of DNA methylation in cancer and aging. Email:

Alice Mouton

Alice Mouton

Dr Alice Mouton is an Assistant Project Scientist in Robert Wayne laboratory in the department of Ecology and Evolutionary Biology. Her current researches focus on applying gene expression methodologies (RNA-seq and RRBS) to study non model organisms (bobcat, island fox) in a context of conservation. Email: amouton@ucla.edu

Serghei Mangul

Serghei Mangul

Dr. Mangul is currently a Postdoctoral Fellow with Eleazar Eskin (Department of Computer Science) at UCLA. Serghei holds a Collaboratory Fellowship from Institute for Quantitative and Computational Biosciences (QCB). His research focuses on developing bioinformatics methods to leverage large-scale high-throughput genomics datasets to better understand the biology of disease. His flagship product is Read Origin Protocol (ROP), a tool for discovering the source of all RNA-Seq reads originated from complex RNA molecules recombined T and B cell receptors and microbial communities. ROP was applied across 1 trillion reads across 10641 samples. Serghei is also interested in bioinformatics education and pedagogy. He is leading an undergraduate research group, focused on genomic research. His philosophy on how to engage undergraduates in genomic research is presented here. Email: serghei@cs.ucla.edu + Website: http://www.sergheimangul.com/

Simon Mitchell

Simon Mitchell

Simon Mitchell is a postdoc in computational systems biology working with Professor Alexander Hoffmann. He is working in constructing mathematical simulations of immune systems and cancer. Prior to joining UCLA, his undergraduate studies in computer science and math led him to a PhD investigating the computational modeling of human iron metabolism at the University of Manchester. Dr. Mitchell’s general interests lie in programming, computational biology, mathematical modeling, sensitivity analyses and translational research. Email: Simon.Mitchell@ucla.edu

Renaud Dessalles

Renaud Dessalles

Dr. Renaud Dessalles is a Post-Doctoral researcher at the laboratory of Biomathematics currently working on the modeling of the immune responses to antigens. His main interested consist in mathematical and computational modeling applied to biology, using mainly (but not exclusively) stochastic models. During his PhD in applied mathematics at INRA and INRIA (France), he worked on the stochastic modeling of protein production inside bacteria. Renaud’s main skills consist of the analysis of stochastic and deterministic models and the use of several computational language (Python, C++, Matlab, Julia) for simulations. Email: dessalles@ucla.edu

Marcus Gallagher-Jones

Marcus Gallagher-Jones

Dr. Marcus Gallagher-Jones is a postdoctoral fellow working in the Rodriguez lab at UCLA. He received his BS in Biochemsitry from Durham University and his PhD in Biophysics from University of Liverpool before working for 2 years in the department of Physics at UCLA. His main interests are in structural analysis across many length-scales (atomic to whole cell) using electron and x-ray diffraction. His expertise include: structural biology, algorithm design, digital image processing, phase retrieval and tomographic reconstruction. Email: marcusgj@chem.ucla.edu

Yerbol Kurmangaliev

Yerbol Kurmangaliev

Dr. Yerbol Kurmangaliev is currently a postdoctoral researcher in the laboratory of Professor S. Lawrence Zipursky. He earned a M.S. degree in Biochemistry at Lomonosov Moscow State University in 2006. He earned a Ph.D. degree in Bioinformatics at Kharkevich Institute for information transmission problems of the Russian Academy of Sciences in 2011 under the supervision of Professor Mikhail S. Gelfand. Before joining to UCLA he was a postdoctoral researcher in the laboratory of Professor Sergey V. Nuzhdin at USC. His previous research interests have been primarily focused on genetic basis of gene expression. Email: ykurmangaliyev@mednet.ucla.edu

Emily Wu

Emily Wu

Dr. Emily Wu is currently an assistant project scientist in the laboratory of Dr. Weizhe Hong in the Department of Biological Chemistry. Her current research interest focuses on applying and developing single-cell RNA sequencing methods and circuit manipulation for the molecular and functional dissection of neural circuitry underlying animal behaviors. She received her B.S. in Biology from Peking University, China. She then earned her Ph.D. from Stanford University where her graduate research focused on molecular and cellular mechanisms governing synapse formation and axonal transport in neurons. Afterwards, she worked as a postdoctoral fellow in Dr. Daniel Geschwind’s lab at UCLA where she investigated the neural mechanisms of autism spectrum disorders through functional genomic and animal behavioral studies. Email: ye.wu@ucla.edu

Ying Zhen

Ying Zhen

Dr. Ying Zhen is a postdoc working with Kirk Lohmueller and Tom Smith. Her research focuses on using NGS data to study the demographic history and natural selection of non-model species from Central Africa. Ying was a postdoc with Peter Andolfatto at Princeton University, working on convergent evolution in insects and gene expression evolution in Drosophila. She received her Ph.D. from Kansas State University where she worked on evolution of freezing tolerance. Email: zhen@g.ucla.edu

Sorel Fitz-Gibbon

Sorel Fitz-Gibbon

Dr. Sorel Fitz-Gibbon is an assistant researcher in the laboratory of Dr. Matteo Pellegrini. Dr. Fitz-Gibbon did her undergraduate work in Molecular, Cell and Developmental Biology at UCLA and also received her Ph.D. there, in Microbiology and Molecular Genetics. Her QCB research is on the bioinformatics aspect of a project to sequence and analyze the genomes of C. reinhardtii laboratory strains.

Fides Lay

Fides Lay

Dr. Fides Lay is a postdoctoral fellow in the laboratory of Dr.Hanna Mikkola. Her current research focuses on elucidating the transcriptional machineries controlling fate commitment and self-renewal during normal hematopoiesis and understanding how these processes are hijacked during leukemogenesis. When not in lab, she enjoys running, kickboxing, going to concerts, eating unhealthy amount of chocolates, and basking in the warm Los Angeles sun.

Thiago Mosqueiro

Thiago Mosqueiro

Dr. Thiago S. Mosqueiro is a Post-Doctoral researcher at the Pinter-Wollman lab (UCLA), primarily working with data analysis and simulations involving learning and behavior of honey bees. His main research interests are mathematical and computational modeling applied to systems biology, especially neuroscience. He received his BS and Ph.D. in Physics from the University of São Paulo (USP). During his Ph.D., he was a visiting graduate student at the BioCircuits Institute (BCI) and the Rady School of Management, at University of California San Diego (UCSD). Thiago has also contributed to research in applied fields, such as Machine Learning, Data Analysis of Chemical Sensors, and Cloud Computing.

Nicholas Mancuso

Nicholas Mancuso

Dr. Nicholas Mancuso is currently a post-doctoral researcher in computational/statistical genetics in Bogdan Pasaniuc’s lab. My research interests include developing computational methods to infer population parameters from low-coverage sequencing data, fine-mapping associations between complex trait and gene expression, and elucidating the role of rare genetic variation in complex traits.

Robert Brown

Robert Brown

Dr. Rob Brown is a post-doctoral researcher working with Sriram Sankararaman and Eleazar Eskin. He completed is BA in astrophysics from Columbia University and his Ph.D. in bioinformatics from UCLA while advised by Bogdan Pasaniuc. As a graduate student, he developed new methods for finding non-linear genetic associations with phenotypes. His current post-doctoral work has two main focuses. The first is to develop surgery outcome predictors using the electronic health records and genotype data from individuals in the UC system. Second, he is interested in understanding how interactions between deleterious coding and regulatory variation shape the genetic architectures and association signals for complex phenotypes.

Bridgett vonHoldt, Ph.D.

Bridgett vonHoldt, Ph.D.

Current Position: Assistant Professor, Princeton University’s Ecology and Evolutionary Biology

Catherine Grasso, Ph.D.

Catherine Grasso, Ph.D.

Current Position: Associate Director, Parker Institute for Cancer Immunotherapy at UCLA

Roberto Spreafico, Ph.D.

Roberto Spreafico, Ph.D.

Current Position: Bioinformatics Scientist, Synthetic Genomics Inc.