TITLE: "Population structure inference for biobank-scale data." ABSTRACT: Inferring the structure of human populations from genetic variation data is a key task in population and medical genomic studies. While a number of methods for population structure inference have been proposed, current methods are impractical to run on biobank-scale genomic datasets containing millions of individuals and […]
Associate Professor of Genetics and of Computer Science, Yale School of Medicine “TBD” Hosted by Jason Ernst
Panelist: Pam Yeh
Assistant Professor of Bioengineering, University of Pennsylvania “Genome folding, unfolding, and refolding in the mammalian brain” Hosted by Hilary Coller
Panelist: Roy Wollman
TITLE: "Mechanisms of robust entrainment of biological oscillators involved in gastric peristalsis.” ABSTRACT: Oscillator entrainment is a widely observed phenomenon in natural systems. Using a computational modeling approach, we decipher the essential intrinsic and extrinsic mechanisms of robust entrainment of biological oscillators involved in gastric peristalsis. Specifically, we show that the constitutive intercellular IP3-facilitated pacemaker […]
TITLE: "Defining chromatin accessibility and molecular dysregulation in Down Syndrome." ABSTRACT: Despite accumulating almost two centuries of medical information, the exact mechanisms underlying Down Syndrome (DS) developmental pathology remain unknown. DS is caused by trisomy of chromosome21 (T21), but without pinpointing the way in which T21 confers molecular dysfunctions and subsequently impairs neurodevelopment, it has been […]
Associate Professor and Vice Chair of Academic Personnel, UCLA Institute for Society and Genetics “Citizen Scientific Racism: White Nationalist Appropriations of Genetic Research” Hosted by Christina Palmer
Panelist: Kirk Lohmueller
