Events for November 3, 2023 - November 6, 2023
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Bioinformatics/Human Genetics Seminar Series: Jennifer Wilson, PhD, Assistant Professor, Bioengineering, UCLA
ZOOM CA, United StatesTITLE: "Deriving network parameters for understanding drug effects.” Hosted by Jason Ernst.
Bioinformatics/Human Genetics Seminar Series: Doc Edge, PhD, Assistant Professor, Quantitative and Computational Biology, USC
ZOOM CA, United StatesTITLE: “The new forensic genetics: 'long-range' search and genetic privacy.” Hosted by Nandita Garud.
QCBio Research Seminar: Xinzhou Ge (Li JJ), Postdoc in Statistics
ZOOM CA, United StatesTITLE: "P-value-free solution to fix exaggerated false positives by popular differential expression methods." ABSTRACT: We report a surprising phenomenon that popular bioinformatics methods for identifying differentially expressed genes (DEG) between two conditions have unexpectedly high false discovery rates (FDRs) on large-sample-size RNA-seq datasets. Failed FDR control is likely due to the invalid p-values which rely on […]
Bioinformatics/Human Genetics Seminar Series: Dana Pe’er, PhD, Chair, Computational and Systems Biology Program, Sloan Kettering Institute
Boyer 159 611 Charles E. Young Dr. E., Los Angeles, CA, United StatesTITLE: "Cellular plasticity in Cancer." Hosted by Jason Ernst.
W10: Mathematical Modeling of Cell Signaling
529 Boyer Hall 611 Charles E Young Dr E,, Los Angeles, CA, United StatesMolecular biology has taught us a great deal about what is happening inside a cell, that is that pathways can get very complicated and life is not just independent pathways but networks. Fortunately, we can use computational tools to understand dynamics of complex networks. This workshop introduces the basic concepts of modeling cell signaling pathways. […]
QCBio Research Seminar: Apeksha Singh (Hoffmann), Graduate Student in Biomathematics
ZOOM CA, United StatesTITLE: "Characterizing distinct cell states based on stimulus-response dynamics." ABSTRACT: Macrophages show remarkable functional pleiotropy that is dependent on microenvironmental context. Prior studies have characterized how polarizing cytokines alter epigenetic or signaling mechanisms, but how they affect specific macrophage functions has not been characterized systematically. One hallmark function of macrophages is to mount immune-threat appropriate […]
QCBio Research Seminar: Richard Law (Park), Graduate Student in Chemical and Biomolecular Engineering
ZOOM CA, United StatesTITLE: "Quantitative flux analysis reveals redistribution of glycolytic pathways in dynamic nutrient environments." ABSTRACT: Optimal operation of metabolic fluxes is critical for an organism to be evolutionarily competitive. Textbook glycolysis is a conserved pathway that optimally utilizes carbohydrates for growth. However, it is unclear why some organisms simultaneously possess the parallel Entner-Doudoroff (ED) pathway, which […]
Bioinformatics/Human Genetics Seminar Series: Leila Jamal, PhD, Genetic Counselor and Bioethicist, Associate Director for Cancer Genomics, National Cancer Institute and the Johns Hopkins Bloomberg School of Public Health
Boyer 159 611 Charles E. Young Dr. E., Los Angeles, CA, United StatesTITLE: “Walking the line between progress and paternalism in genetic counseling.” Hosted by Christina Palmer.
QCBio Research Seminar: Matthew Heffel (Luo), Graduate Student in Bioinformatics
ZOOM CA, United StatesTITLE: "Multimodal Single-Cell Epigenomic Sequencing of the Developing Human Cerebral Cortex." ABSTRACT: Single cell epigenomic technologies allow the measurement of unique molecular signatures within cells, however cell type complexity remains highly enigmatic. Emerging methods have enabled multiple modalities of epigenomic sequencing to be gathered from the same cell. Single-nucleus methyl-3C sequencing (sn-m3C-seq) delivers the capacity to […]
