Calendar of Events
Calendar of Events
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2 events,
QCBio Research Seminar: Amelia Palermo (Graeber)
QCBio Research Seminar: Amelia Palermo (Graeber)
TITLE: "Metabolic dependencies of ecDNA and HSR focal amplification modes and plasticity." ABSTRACT: The focal amplification (FA) of genes that support the uncontrolled growth and proliferation of cells (i.e., oncogenes) on homogeneous chromosomal staining regions (HSRs, chromosomal) ans extrachromosomal DNA (ecDNA) is a hallmark of resistant cancers. However, it remains an open question whether oncogene […]
QCBio Research Seminar: Nan (Miles) Xi (Li JJ)
QCBio Research Seminar: Nan (Miles) Xi (Li JJ)
TITLE: "DoubletCollection: An R package that integrates cutting-edge computational doublet-detection methods." ABSTRACT: The existence of doublets is a key confounder in single-cell RNA sequencing (scRNA-seq) data analysis. There are several computational methods for detecting doublets from scRNA-seq data. We develop an R package DoubletCollection to integrate the installation and execution of those methods. DoubletCollection also […]
1 event,
QCBio Research Seminar in collaboration with B.I.G. Summer: Jingyi Jessica Li
QCBio Research Seminar in collaboration with B.I.G. Summer: Jingyi Jessica Li
TITLE: “Applications of generalized additive models and copulas to single-cell RNAseq computational method development: PseudotimeDE and scDesign2” ABSTRACT: Part 1: PseudotimeDE: inference of differential gene expression along cell pseudotime with well-calibrated p-values from single-cell RNA sequencing data To investigate molecular mechanisms underlying cell state changes, a crucial analysis is to identify differentially expressed (DE) genes […]
