QCBio Research Seminar: Chloe Yap (Gandal), Visiting Graduate Student, University of Queensland

Boyer 159 611 Charles E. Young Dr. E., Los Angeles, CA, United States

TITLE: "Restricted diet drives autism gut-microbiome associations, and other tales from the Australian Autism Biobank" ABSTRACT: The Australian Autism Biobank (AAB) is an initiative of the Autism CRC – the first national, cooperative research effort focused on autism across the lifespan. The AAB recruited a total of ~2,500 autistic children, family members, and unrelated undiagnosed […]

QCBio Research Seminar: Paheli Desai-Chowdhry (Savage), Grad student in Biomathematics

Boyer 159 611 Charles E. Young Dr. E., Los Angeles, CA, United States

TITLE: "Asymmetric Branching Scale Factors as Features in Neuronal Cell-Type Classification" ABSTRACT: Neurons are connected by complex branching processes - axons and dendrites - that process information for organisms to respond to their environment. Classifying neurons according to differences in structure or function is a fundamental piece of neuroscience. In previous work, we constructed a […]

QCBio Research Seminar: Jee Yun Han (Boutros), Graduate Student in MBIDP (Molecular Biology Interdepartmental Doctoral Program)

ZOOM CA, United States

TITLE: "Comprehensive study of gene expression outliers and their regulation mechanisms in pan-cancer." ABSTRACT: With the ultimate aim of improving the management of cancer, many groups have studied the molecular characteristics of tumors. Typically, the heterogeneity of cancer evolves rapidly to adapt to its microenvironment, helping cancer evade selective pressures and progress. These various subclones […]

QCBio Research Seminar: Jianxiao Yang (Suchard), Grad Student in Biomathematics

ZOOM CA, United States

TITLE: "Massive parallelization of massive sample-size survival analysis." ABSTRACT: Large-scale observational health databases are increasingly popular for conducting comparative effectiveness and safety studies of medical products. However, increasing number of patients poses computational challenges when fitting survival regression models in such studies. In this paper, we use graphics processing units (GPUs) to parallelize the computational bottlenecks of […]

QCBio Research Seminar: Evan Maltz (Wollman), Graduate Student in BMSB (Biochemistry, Molecular and Structural Biology)

ZOOM CA, United States

TITLE: "Phenotypic consequences of gene expression variability." ABSTRACT: The central dogma of biology proposes that information flows from genes to RNA to protein, determining protein identity and abundance. Single cell transcriptome measurements provide ample information about RNA abundance in cells. While the expression of individual genes clearly matters for determining phenotype, they do not work […]