Events for December 2, 2022 - May 11, 2022

TITLE: "Quantitative flux analysis reveals redistribution of glycolytic pathways in dynamic nutrient environments." ABSTRACT: Optimal operation of metabolic fluxes is critical for an organism to be evolutionarily competitive. Textbook glycolysis is a conserved pathway that optimally utilizes carbohydrates for growth. However, it is unclear why some organisms simultaneously possess the parallel Entner-Doudoroff (ED) pathway, which […]

TITLE: “Walking the line between progress and paternalism in genetic counseling.” Hosted by Christina Palmer.

TITLE: "Multimodal Single-Cell Epigenomic Sequencing of the Developing Human Cerebral Cortex." ABSTRACT: Single cell epigenomic technologies allow the measurement of unique molecular signatures within cells, however cell type complexity remains highly enigmatic. Emerging methods have enabled multiple modalities of epigenomic sequencing to be gathered from the same cell. Single-nucleus methyl-3C sequencing (sn-m3C-seq) delivers the capacity to […]

TITLE: "moPepGen: a fast custom database generator from multi-omics data for proteogenomics." ABSTRACT: Cancers are driven by genomic variants such as SNV (single nucleotide variants) and INDEL, often accompanied by many transcriptional variants. Modern mass spectrometry based proteomics is able to identify and quantify peptides and proteins comprehensively, however the variant-harboring peptides that are absent […]

TITLE: "Automated genetic analysis" Hosted by Nandita Garud.

TITLE: "Genomics for precision public health in Colombia" Hosted by Juan De La Hoz.

TITLE: "G-Flux: a metabolic flux and free energy analysis software for interpreting 13C, 2H, 18O, and 15N isotope tracing data." ABSTRACT: Metabolic fluxes offer insights into pathway utilization, kinetics, and thermodynamics. Stable isotope tracing and metabolic footprinting are widely used for inferring metabolic fluxes. However, quantitative flux measurement across broad metabolism remains challenging due to […]