TITLE: "A simple, two-step, multivalent binding model predicts IL-2 mutein cell signaling profiles." ABSTRACT: The common γ-chain cytokines are promising immune therapies, but have been limited in their efficacy due to […]
TITLE: "Multimodal radiomic analysis of biparametric MRI to predict biochemical recurrence after radical prostatectomy." ABSTRACT: Integration of information across multiple modalities and biological scales has the potential to improve the prediction […]
Associate director, Gerstner Center for Cancer Diagnostics, Broad Institute “Ultrasensitive detection of minimal residual disease” Hosted by Jasmine Zhou
Panelist: Paul Boutros
TITLE: "Genome-wide survey of mutations influencing protein abundances in yeast" ABSTRACT: Our understanding of how protein-level regulation is encoded in the genome and how protein abundances are affected by DNA […]
TITLE: "Unbiased analysis of single cell RNA sequencing data reveals previously uncharacterized heterogeneity in small cell lung cancer cell lines." ABSTRACT: Small Cell Lung Cancer (SCLC) accounts for approximately 13% […]
Associate Professor, Biostatistics & Bioinformatics, Center for Genomic and Computational Biology, Duke University “TBD” Hosted by Jason Ernst
Panelist: Emilie Marcus
TITLE: “Large uncertainty in individual PRS estimation impacts PRS-based risk stratification.” ABSTRACT: Large-scale genome-wide association studies have enabled polygenic risk scores (PRS), which estimate the genetic value of an individual […]
TITLE: "Constructing a Functional Interactome from Published Work to Identify Underrepresented and Integrative Effects of Neuroinflammatory Cytokines on Neural Excitability." ABSTRACT: Maintaining normal excitability is a key function of our […]
