TITLE: "Metabolic dependencies of ecDNA and HSR focal amplification modes and plasticity." ABSTRACT: The focal amplification (FA) of genes that support the uncontrolled growth and proliferation of cells (i.e., oncogenes) […]
TITLE: "DoubletCollection: An R package that integrates cutting-edge computational doublet-detection methods." ABSTRACT: The existence of doublets is a key confounder in single-cell RNA sequencing (scRNA-seq) data analysis. There are several […]
TITLE: “Applications of generalized additive models and copulas to single-cell RNAseq computational method development: PseudotimeDE and scDesign2” ABSTRACT: Part 1: PseudotimeDE: inference of differential gene expression along cell pseudotime with […]
TITLE: “Integrating single cell omics and deep phenotype data to discover genes underlying cardiometabolic disorders” ABSTRACT: Obesity predisposes to cardiometabolic disorders (CMDs), such as type 2 diabetes, multiple dyslipidemias, and […]
TITLE: "Is there a Quiescence Histone Code?" ABSTRACT: Many of the cells in our bodies are quiescent, that is, temporarily not dividing. Under certain physiological conditions such as during tissue repair […]
TITLE: “Model driven design and analysis of quantitative phenotype screens” ABSTRACT: Increasingly, CRISPR screens are coupled with flow cytometry (FACS) to sort cells and quantify the impact of genetic perturbations on a continuous […]
TITLE: “Salivary exRNA for Gastric Cancer Detection” ABSTRACT: Biomarkers are needed for non-invasive early detection of gastric cancer (GC). We investigated whether salivary extracellular RNA (exRNA) biomarkers can be used as an efficient and […]
TITLE: “From Bench to Vending Machine: Development and Deployment of Novel Diagnostic testing for SARS-CoV-2 using Genomic Technology” ABSTRACT: Frequent and widespread testing of members of the population who are asymptomatic for severe […]
“Genetic and environmental effects on chromatin accessibility at cardiometabolic trait loci” Hosted by Paivi Pajukanta
“Omic insights into Andean high-altitude adaptation” Hosted by Jason Ernst
